Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes
作者:Peng Du、Uma M. Viswanathan、Khairan Khairan、Tomislav Buric、Nathaniel E. B. Saidu、Zhanjie Xu、Benjamin Hanf、Inga Bazukyan、Armen Trchounian、Frank Hannemann、Ingolf Bernhardt、Torsten Burkholz、Britta Diesel、Alexandra K. Kiemer、Karl-Herbert Schäfer、Mathias Montenarh、Gilbert Kirsch、Claus Jacob
DOI:10.1039/c3md00204g
日期:——
Several amphiphilic, chalcogen-based redox modulators have been synthesized which exhibit a widespread, yet in some instances also selective, biological activity which is most likely based on their ability to modulate the intracellular redox balance and to interact with cellular membranes and specific proteins.