N,N'-Bis-[2-(toluene-4-sulfonylamino)-phenyl]-malonamide | 201297-17-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-Bis-[2-(toluene-4-sulfonylamino)-phenyl]-malonamide
• 英文别名: N,N'-bis[2-[(4-methylphenyl)sulfonylamino]phenyl]propanediamide
• CAS: 201297-17-8
• 化学式: C₂₉H₂₈N₄O₆S₂
• 分子量: 592.697
• InChiKey: FLZOIROWFCSHBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  41
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  167
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  N,N'-Bis-[2-(toluene-4-sulfonylamino)-phenyl]-malonamide 在 四丁基碘化铵 作用下， 以 乙腈 为溶剂， 以30%的产率得到N,N'-Bis-(2-amino-phenyl)-malonamide
  参考文献：
  名称：

  Decisive role of Al3+ cation in the electrodetosylation of N, N′-bis-(o-tosylaminophenyl) propanediamide to N, N′-bis-(o-aminophenyl) propanediamide

  摘要：

  The reductive electrodetosylation of N,N'-bis-(o-tosylaminophenyl) propanedlamide was performed in an undivided cell fitted with a sacrificial aluminum anode, at constant current and a: room temperature. The completion of the reduction process was favoured by the complexing effect of the anodically generated metal ion to form Al - N, N'-bis (o-aminophenyl) propanediamide. Finally, the N, N'-bis (o-aminophenyl) propanediamide is obtained by hydrolysis of the Al - complex. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)10095-3
• 作为产物：
  描述：

  N-(2-氨基苯基)-4-甲基苯磺酰胺 、 丙二酰氯 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 48.0h， 以78%的产率得到N,N'-Bis-[2-(toluene-4-sulfonylamino)-phenyl]-malonamide
  参考文献：
  名称：

  Decisive role of Al3+ cation in the electrodetosylation of N, N′-bis-(o-tosylaminophenyl) propanediamide to N, N′-bis-(o-aminophenyl) propanediamide

  摘要：

  The reductive electrodetosylation of N,N'-bis-(o-tosylaminophenyl) propanedlamide was performed in an undivided cell fitted with a sacrificial aluminum anode, at constant current and a: room temperature. The completion of the reduction process was favoured by the complexing effect of the anodically generated metal ion to form Al - N, N'-bis (o-aminophenyl) propanediamide. Finally, the N, N'-bis (o-aminophenyl) propanediamide is obtained by hydrolysis of the Al - complex. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)10095-3

文献信息

• Decisive role of Al3+ cation in the electrodetosylation of N, N′-bis-(o-tosylaminophenyl) propanediamide to N, N′-bis-(o-aminophenyl) propanediamide
  作者：Y.W. Lu

  DOI：10.1016/s0040-4020(97)10095-3

  日期：1997.12

  The reductive electrodetosylation of N,N'-bis-(o-tosylaminophenyl) propanedlamide was performed in an undivided cell fitted with a sacrificial aluminum anode, at constant current and a: room temperature. The completion of the reduction process was favoured by the complexing effect of the anodically generated metal ion to form Al - N, N'-bis (o-aminophenyl) propanediamide. Finally, the N, N'-bis (o-aminophenyl) propanediamide is obtained by hydrolysis of the Al - complex. (C) 1997 Elsevier Science Ltd.