isopropyl trans-2-phenylvinyl ether | 70064-30-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: isopropyl trans-2-phenylvinyl ether
• 英文别名: [2-(1-methylethoxy)-ethenyl]-benzene；beta-Isopropoxystyrene, (E)；[(E)-2-propan-2-yloxyethenyl]benzene
• CAS: 70064-30-1
• 化学式: C₁₁H₁₄O
• 分子量: 162.232
• InChiKey: VNOSMVIVSUHSPU-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,2-dimethylethylene hydrogen phosphite 、 isopropyl trans-2-phenylvinyl ether 生成 2-(1-Isopropoxy-2-phenyl-ethyl)-4,5-dimethyl-[1,3,2]dioxaphospholane 2-oxide
  参考文献：
  名称：

  OVCHINNIKOV, V. V.;CHEREZOV, S. V.;CHERKASOV, R. A.;PUDOVIK, A. N., ZH. OBSHCH. XIMII, 1984, 54, N 5, 1021-1030

  摘要：

  DOI：
• 作为产物：
  描述：

  1,1-二甲氧基-2-苯基乙烷 在 对甲苯磺酸 作用下， 生成 isopropyl trans-2-phenylvinyl ether
  参考文献：
  名称：

  Taylor, Roger, Journal of the Chemical Society. Perkin transactions II, 1988, p. 737 - 744

  摘要：

  DOI：

文献信息

• RECYCLABLE METATHESIS CATALYSTS
  申请人：Trustees of Boston College, The

  公开号：US20160168181A1

  公开（公告）日：2016-06-16

  Highly active, recoverable and recyclable transition metal-based metathesis catalysts and their organometallic complexes including dendrimeric complexes are disclosed, including a Ru complex bearing a 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene and styrenyl ether ligand. The heterocyclic ligand significantly enhances the catalytic activity, and the styrenyl ether allows for the easy recovery of the Ru complex. Derivatized catalysts capable of being immobilized on substrate surfaces are also disclosed. The present catalysts can be used to catalyze ring-closing metathesis (RCM), ring-opening (ROM) and cross metatheses (CM) reactions, and promote the efficient formation of various trisubstituted olefins at ambient temperature in high yield.

  高度活性、可回收和可循环使用的过渡金属基催化剂及其有机金属络合物，包括树枝状络合物被披露，包括一种带有1,3-二甲基-4,5-二氢咪唑-2-亚基和苯乙烯基醚配体的钌络合物。杂环配体显著提高了催化活性，而苯乙烯基醚使得钌络合物易于回收。还披露了能够固定在底物表面的衍生催化剂。所述催化剂可用于催化环闭合烯烃复分解反应(RCM)、环开环反应(ROM)和交叉复分解反应(CM)，并在室温下高效地促进各种三取代烯烃的高产形成。
• Practical regioselective synthetic method for (E)-enol ether
  作者：Hyeung-geun Park、Dong-Hwa Kim、Misuk You、Mi-kyoung Park、Sang-sup Jew

  DOI：10.1016/s0040-4039(00)00603-1

  日期：2000.6

  A new practical and highly regioselective synthetic method for (E)-enol ether is reported. (E)-enol ethers (E:Z=93:7–99:1) were prepared from the corresponding enol acetates (E:Z≅3:1) in two steps by bromination and anti-elimination of α-bromodialkylacetal via metal halogen exchange.

  报道了一种新的实用且高度区域选择性的（E）-烯醇醚合成方法。（É）烯醇醚类（Ë：ž = 93：7-99：1）从相应的烯醇乙酸酯（其制备ê：ž在两个步骤由溴化和经由金属α-bromodialkylacetal的抗消除：≅31）卤素交换。
• SYNTHESIS OF (S)-2-ACETAMIDO-3-(4-HYDROXY-3-(3-METHYLBUT-2-ENYL) PHENYL) PROPANOIC ACID DERIVATIVES
  申请人：King Fahd University of Petroleum and Minerals

  公开号：US20170114004A1

  公开（公告）日：2017-04-27

  A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is disclosed. The method proceeds through an O-allylated tyrosine-based compound, such as compound 3 and preferably comprises [3,3] sigmatropic Claisen rearrangement and olefin cross metathesis reactions. In addition, a pharmaceutical composition comprising a compound of formula (I) a tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) and a pharmaceutically acceptable carrier or excipient is disclosed.

  本发明公开了一种制备式(I)化合物或其药学上可接受的盐、溶剂化物、互变异构体或立体异构体的方法，例如化合物1和化合物2。该方法通过一种O-烯丙基化的基于酪氨酸的化合物，例如化合物3进行，最好包括[3,3]sigmatropic Claisen重排和烯烃交叉重聚反应。此外，本发明还公开了一种包含式(I)化合物、肿瘤坏死因子(TNF)相关的凋亡诱导配体(TRAIL)和药学上可接受的载体或赋形剂的制药组合物。
• Alkenylphenol- und Alkenylphenolether-Copolymere
  申请人：SIEMENS AKTIENGESELLSCHAFT

  公开号：EP0283764A1

  公开（公告）日：1988-09-28

  Die Erfindung betrifft neue Alkenylphenol-Copolymere bzw. deren Ether. Die Copolymeren nach der Erfindung sind Alkenylphenol- ­bzw. Alkenylphenolether-Alkenylsilan-Copolymere der allge­meinen Formel: Photoresists

  本发明涉及新的烯基苯酚共聚物或其醚。 根据本发明，共聚物是通式为： 光阻的烯基苯酚或烯基苯酚醚-烯基硅烷共聚物。
• Ruthenium complex ligand, ruthenium complex and the use of the complex as a catalyst in olefin metathesis reactions
  申请人：Zannan Scitech Co., Ltd.

  公开号：EP2886549A1

  公开（公告）日：2015-06-24

  The present invention disclosed a kind of ruthenium complex ligands, ruthenium complexes and immobilized ruthenium complex catalysts. The invention also relates to preparation and use of new ruthenium complex ligands and ruthenium complexes in metathesis reactions as catalysts have several significant advantages, e.g., high catalytic activity, high stability, easy recovery and reusability. The ruthenium complex ligand I and ruthenium complex II in the present invention have the following structures:

  本发明公开了一种钌络合物配体、钌络合物和固定化钌络合物催化剂。本发明还涉及新型钌络合物配体和钌络合物的制备和在偏析反应中的使用，作为催化剂，新型钌络合物和钌络合物具有催化活性高、稳定性强、易于回收和重复使用等显著优点。本发明中的钌络合物配体 I 和钌络合物 II 具有如下结构：