(RS,SR)-N,N'-diallyl-1,2-di(4-methylphenyl)-1,2-ethanediamine | 219517-93-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (RS,SR)-N,N'-diallyl-1,2-di(4-methylphenyl)-1,2-ethanediamine
• 英文别名: (R,S)-N,N'-diallyl-1,2-di(4-methylphenyl)-1,2-ethylenediamine；(1R,2S)-1,2-bis(4-methylphenyl)-N,N'-bis(prop-2-enyl)ethane-1,2-diamine
• CAS: 219517-93-8
• 化学式: C₂₂H₂₈N₂
• 分子量: 320.478
• InChiKey: CQPGGTDICVQYOB-SZPZYZBQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-(4-methylbenzylidene)allylamine 在 氢化铝 咪唑 、 二氯化二茂钒 、 苯基二甲基氯硅烷 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 生成 (RS,SR)-N,N'-diallyl-1,2-di(4-methylphenyl)-1,2-ethanediamine 、 (RS,RS)-N,N'-diallyl-1,2-di(4-methylphenyl)-1,2-ethanediamine
  参考文献：
  名称：

  A Catalytic System Consisting of Vanadium, Chlorosilane, and Aluminum Metal in the Stereoselective Pinacol Coupling Reaction of Benzaldehyde Derivatives

  摘要：

  DOI：

  10.1021/jo990902m

文献信息

• Cp₂VCl₂-Catalyzed Meso-Selective Pinacol Coupling Reaction of Aldimines in the Presence of Chlorosilane and Zinc Metal
  作者：Bunpei Hatano、Akiya Ogawa、Toshikazu Hirao

  DOI：10.1021/jo981396o

  日期：1998.12.1

  A catalytic reductive coupling of aldimines was achieved by using a catalyst Cp(2)VCl(2)/PhMe(2)SiCl/Zn system. The influence of the catalyst, chlorosilane, co-reductant, solvent, and temperature on both the yield and diastereoselectivity of the coupling products was investigated in detail. As a result, the present Cp(2)VCl(2)-catalyzed reductive coupling of aldimines in the presence of PhMe(2)SiCl and zinc metal provided the corresponding 1,2-diamines in good yield with high meso selectivity (up to 92% meso), while the reductive coupling of aldehydes, ketones, and aldimines by the hitherto known catalytic methods leads to the preferential formation of dl isomers of the coupling products.
• A Catalytic System Consisting of Vanadium, Chlorosilane, and Aluminum Metal in the Stereoselective Pinacol Coupling Reaction of Benzaldehyde Derivatives
  作者：Toshikazu Hirao、Bunpei Hatano、Yuka Imamoto、Akiya Ogawa

  DOI：10.1021/jo990902m

  日期：1999.10.1