1-(4-iodophenyl)-1-propanol | 90609-48-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4-iodophenyl)-1-propanol
• 英文别名: 1-(4-Iod-phenyl)-propanol-(1)；1-(4-iodo-phenyl)-propan-1-ol；1-(4-Jod-phenyl)-propan-1-ol；1-(4-Iodophenyl)propan-1-ol
• CAS: 90609-48-6
• 化学式: C₉H₁₁IO
• 分子量: 262.09
• InChiKey: WHVOBMQSOGUJIK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(4-iodophenyl)-1-propanol 在 乙醚 、 phosphorus pentoxide 作用下， 生成 1-iodo-4-(ξ-propenyl)-benzene
  参考文献：
  名称：

  Frejka; Zamis, 1950, vol. 63, p. 157

  摘要：

  DOI：
• 作为产物：
  描述：

  4-碘苯丙酮 在 aluminum isopropoxide 、 异丙醇 作用下， 生成 1-(4-iodophenyl)-1-propanol
  参考文献：
  名称：

  一类新的降胆固醇药：芳基烷基琥珀酸氢盐和戊二酸。

  摘要：

  DOI：

  10.1021/jm50019a003

文献信息

• Catalytic Enantioselective Amination of Enol Silyl Ethers Using a Chiral Paddle-Wheel Diruthenium Complex
  作者：Kotoko Makino、Yuhei Kumagai、Tatsuhiko Yoshino、Masahiro Kojima、Shigeki Matsunaga

  DOI：10.1021/acs.orglett.3c00940

  日期：2023.5.12

  applied to a catalytic asymmetric nitrene-transfer reaction with enol silyl ethers. The ruthenium catalyst was applicable to aliphatic enol silyl ethers as well as aryl-containing enol silyl ethers. The substrate scope of the ruthenium catalyst was superior to that of analogous chiral paddle-wheel rhodium catalysts. α-Amino ketones derived from aliphatic substrates were obtained in up to 97% ee with the

  将手性桨轮双核钌催化剂应用于与烯醇甲硅烷基醚的催化不对称氮烯转移反应。钌催化剂适用于脂肪族烯醇硅醚以及含芳基的烯醇硅醚。钌催化剂的底物范围优于类似的手性桨轮铑催化剂。使用钌催化剂可获得高达 97% ee 的源自脂肪族底物的 α-氨基酮，而类似的铑催化剂仅产生适度的对映选择性。
• Selective Halogen−Magnesium Exchange Reaction via Organomagnesium Ate Complex
  作者：Atsushi Inoue、Kazuya Kitagawa、Hiroshi Shinokubo、Koichiro Oshima

  DOI：10.1021/jo015597v

  日期：2001.6.1

  Halogen-magnesium exchange of various aryl halides is achieved with a magnesium ate complex at low temperatures; Tributylmagnesate ((Bu3MgLi)-Bu-n) induces facile iodine-magnesium exchange at -78 degreesC. Dibutylisopropylmagnesate ((PrBu2MgLi)-Pr-i-Bu-n) is more reactive than (Bu3MgLi)-Bu-n, and this reagent accomplishes selective bromine-magnesium exchange at -78 degreesC. This procedure is utilized for the preparation of various polyfunctionalized arylmagnesium species. The exchange of alkenyl halides using this method proceeds with retention of configuration of the double bond.
• Structurally constrained C1-1,1′-bisisoquinoline-based chiral ligands: geometrical implications on enantioinduction in the addition of diethylzinc to aldehydes
  作者：Gao Qi、Zaher M.A. Judeh

  DOI：10.1016/j.tetasy.2010.02.022

  日期：2010.3

  New highly constrained chiral C-1-1,1'-bisisoquinoline ligands have been synthesized. X-ray crystallographic analysis of these ligands showed peculiar structural differences between the parent 1',2',3',4'-tetrahydro-1,1'-bisisoquinoline and its alkyl, acyl and sulfonyl derivatives. The consequences of their geometrical conformations on enantioinduction were examined by employing the enantioselective addition of diethylzinc to aldehydes. Such conformations greatly affected the catalytic efficiency of these ligands. (C) 2010 Elsevier Ltd. All rights reserved.
• COMPOSITION FOR FORMING RESIST UNDERLAYER
  申请人：AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L.

  公开号：US20150118624A1

  公开（公告）日：2015-04-30

  The present invention provides a dendrimer compound capable of improving critical dimension uniformity and DOF (depth of focus) margin, and also provides a composition capable of forming an underlayer film. The dendrimer compound comprises a branched chain having a central aromatic skeleton and amide or ester bond, and is contained in the composition for forming an underlayer film.
• US9328198B2
  申请人：——

  公开号：US9328198B2

  公开（公告）日：2016-05-03