3,2'-trimethylene-2-phenylbenzo[b]-1,10-phenanthroline | 952652-57-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并环庚烷吡啶
• 英文名称: 3,2'-trimethylene-2-phenylbenzo[b]-1,10-phenanthroline
• 英文别名: 2,26-Diazahexacyclo[13.12.0.03,13.04,9.018,27.020,25]heptacosa-1,3(13),4,6,8,14,16,18,20,22,24,26-dodecaene；2,26-diazahexacyclo[13.12.0.03,13.04,9.018,27.020,25]heptacosa-1,3(13),4,6,8,14,16,18,20,22,24,26-dodecaene
• CAS: 952652-57-2
• 化学式: C₂₅H₁₈N₂
• 分子量: 346.431
• InChiKey: YMIKYHABNQIESH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  27
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  ammonium hexafluorophosphate 、 3,2'-trimethylene-2-phenylbenzo[b]-1,10-phenanthroline 、 Ru(tpy)(Cl)₃ 在 三乙胺 作用下， 以 乙醇 、 水 为溶剂， 反应 12.0h， 以30%的产率得到
  参考文献：
  名称：

  Studies on the reactions of 3,2′-polymethylene-2-phenylbenzo[b]-1,10-phenanthrolines with Ru(tpy)Cl3 and properties of the products

  摘要：

  中的质粒（100μM）在空气中8c（λirr>395nm，10min）存在下的照射。

  DOI：

  10.1007/s12272-017-0894-1
• 作为产物：
  描述：

  1-苯并环庚酮 、 4-aminoacridine-3-carbaldehyde 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 12.0h， 以69%的产率得到3,2'-trimethylene-2-phenylbenzo[b]-1,10-phenanthroline
  参考文献：
  名称：

  Rahman, A.F.M. Motiur; Jahng, Yurngdoag, Heterocycles, 2007, vol. 71, # 9, p. 2003 - 2010

  摘要：

  DOI：

文献信息

• Rahman, A.F.M. Motiur; Jahng, Yurngdoag, Heterocycles, 2007, vol. 71, # 9, p. 2003 - 2010
  作者：Rahman, A.F.M. Motiur、Jahng, Yurngdoag

  DOI：——

  日期：——
• Studies on the reactions of 3,2′-polymethylene-2-phenylbenzo[b]-1,10-phenanthrolines with Ru(tpy)Cl3 and properties of the products
  作者：Yang Lu、A. F. M. Motiur Rahman、Yurngdong Jahng

  DOI：10.1007/s12272-017-0894-1

  日期：2017.5

  A series of 3,2-polymethylene-2-phenylbenzo[b]-1,10-phenanthrolines was reacted with Ru(tpy)Cl3 to afford two ruthenium (Ru) complexes, a pentaaza-coordinated (N5Cl) complex [Ru(tpy)(L)Cl]+ and a hexa-coordinated (N5C) complex [Ru(tpy)(L)]+. The ratio of these two complexes was found to be highly dependent on the length of the polymethylene bridge between terminal phenyl and central pyridine rings. The reaction between the dimethylene-bridged ligand and Ru(tpy)Cl3 afforded a hexa-coordinated (N5C) complex as an only isolatable product in 83% yield, while the others afforded pentaaza-coordinated products and hexa-coordinated products in ratios of 1:1.6–3.5 with 80–90% overall yields. The UV spectra of pentaaza-coordinated complexes (N5Cl) and hexa-coordinated (N5C) cycloruthenated complexes were similar to show absorbances at 253–255, 276–286, 312–324, 360–373, and 490–532 nm. All of these complexes showed greenish blue light emissions in the range 450–460 nm upon excitation in the range 368–382 nm, while excitation at 500-532 nm resulted in green light emissions at 570 nm for pentaaza-coordinated complexes and 577–579 nm for hexaaza-coordinated species. Irradiation of the plasmid (100 μM) in the presence of 8c (λirr > 395 nm, 10 min) in air resulted in single-strand cleavage leading to the production of nicked plasmid (Form II), probably via intercalation.

  中的质粒（100μM）在空气中8c（λirr>395nm，10min）存在下的照射。