N-[(3-溴苯基)甲基]丁胺 | 60509-39-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-[(3-溴苯基)甲基]丁胺
• 中文别名: (3-溴苄基)丁基-1-胺
• 英文名称: Benzenemethanamine, 3-bromo-N-butyl-
• 英文别名: N-[(3-bromophenyl)methyl]butan-1-amine
• CAS: 60509-39-9
• 化学式: C₁₁H₁₆BrN
• mdl: MFCD07409983
• 分子量: 242.159
• InChiKey: WBAYBKZTZNUUAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2921499090

反应信息

• 作为产物：
  描述：

  3-溴苄溴 、 正丁胺 以 硝基苯 为溶剂， 生成 N-[(3-溴苯基)甲基]丁胺
  参考文献：
  名称：

  Shpan'ko, I. V.; Korostylev, A. P.; Rusu, L. N., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, p. 1715 - 1723

  摘要：

  DOI：

文献信息

• Shpan'ko, I. V.; Serebryakov, I. M.; Korostylev, A. P., Journal of Organic Chemistry USSR (English Translation), 1988, vol. 24, # 7, p. 1224 - 1230
  作者：Shpan'ko, I. V.、Serebryakov, I. M.、Korostylev, A. P.

  DOI：——

  日期：——
• NARGENICIN COMPOUNDS AND USES THEREOF AS ANTIBACTERIAL AGENTS
  申请人：Merck Sharp & Dohme Corp.

  公开号：US20180186808A1

  公开（公告）日：2018-07-05

  The present invention relates to novel nargenicin related compounds which can inhibit DnaE and have antibacterial, particularly antimycobacterial activity against Mycobacterium tuberculosis . The present invention also relates to method for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis by administering an antimycobacterially effective amount of nargenicin or a nargenicin-related compound and/or their pharmaceutically acceptable salts.
• [EN] LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME<br/>[FR] BIBLIOTHÈQUES DE DIVERS COMPOSÉS MACROCYCLIQUES, LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
  申请人：CYCLENIUM PHARMA INC

  公开号：WO2017197488A1

  公开（公告）日：2017-11-23

  The present disclosure relates to novel macrocyclic compounds and libraries thereof that are useful as research tools for drug discovery efforts. This disclosure also relates to methods of preparing these compounds and libraries and methods of using these libraries, such as in high throughput screening. In particular, these libraries are useful for evaluation of bioactivity at existing and newly identified pharmacologically relevant targets, including G protein-coupled receptors, nuclear receptors, enzymes, ion channels, transporters, transcription factors, protein-protein interactions and nucleic acid-protein interactions. As such, these libraries can be applied to the search for new pharmaceutical agents for the treatment and prevention of a range of medical conditions.
• Shpan'ko, I. V.; Korostylev, A. P.; Rusu, L. N., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, p. 1715 - 1723
  作者：Shpan'ko, I. V.、Korostylev, A. P.、Rusu, L. N.

  DOI：——

  日期：——