p-t-Butylphenylchloracetat | 6291-99-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: p-t-Butylphenylchloracetat
• 英文别名: (p-tert-Butyl-phenyl)-monochloracetat；chloro-acetic acid-(4-tert-butyl-phenyl ester)；Chlor-essigsaeure-(4-tert-butyl-phenylester)；4-Tert-butylphenyl chloroacetate；(4-tert-butylphenyl) 2-chloroacetate
• CAS: 6291-99-2
• 化学式: C₁₂H₁₅ClO₂
• 分子量: 226.703
• InChiKey: PYLFASLKMVYXQY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-叔丁基苯酚 、 氯乙酰氯 在 magnesium 、 苯 作用下， 生成 p-t-Butylphenylchloracetat
  参考文献：
  名称：

  Tiwari; Singh, Journal of the Indian Chemical Society, 1959, vol. 36, p. 801

  摘要：

  DOI：

文献信息

• Kamennov,N.A. et al., Journal of applied chemistry of the USSR, 1967, vol. 40, # 3, p. 624 - 627
  作者：Kamennov,N.A. et al.

  DOI：——

  日期：——
• Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof
  申请人：Burnett A. Duane

  公开号：US20070155675A1

  公开（公告）日：2007-07-05

  The present invention provides substituted azetidinone compounds, formulations and processes for preparing the same which can be useful for treating vascular conditions such as atherosclerosis or hypercholesterolemia, diabetes, obesity, stroke, demyelination and lowering plasma levels of sterols and/or stanols in a subject.
• Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
  申请人：Burnett Duane A.

  公开号：US20080207585A1

  公开（公告）日：2008-08-28

  The present invention provides compounds represented by the structural formula (I): or pharmaceutically acceptable isomers, salts, solvates or esters of the compound of Formula (I), wherein each of the substituents is as specified herein, formulations including the above compounds, processes for preparing the same and methods for treating atherosclerosis, hypercholesterolemia, or sitosterolemia, and for lowering plasma levels of sterols and/or stanols.
• US7235543B2
  申请人：——

  公开号：US7235543B2

  公开（公告）日：2007-06-26
• US7368563B2
  申请人：——

  公开号：US7368563B2

  公开（公告）日：2008-05-06