(R)-5,5'-(NHC(O)Ph)2-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl | 244260-30-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (R)-5,5'-(NHC(O)Ph)2-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
• 英文别名: N-[6-diphenylphosphanyl-5-[2-diphenylphosphanyl-5-[[hydroxy(phenyl)methylidene]amino]naphthalen-1-yl]naphthalen-1-yl]benzenecarboximidic acid
• CAS: 244260-30-8
• 化学式: C₅₈H₄₂N₂O₂P₂
• 分子量: 860.931
• InChiKey: XYHOTXPTURKIAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.1
• 重原子数：
  64
• 可旋转键数：
  11
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  65.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dichloro(p-cymene)ruthenium(II) dimer 、 (R)-5,5'-(NHC(O)Ph)2-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl 、 (1R,2R)-1,2-二苯基乙二胺 以 N,N-二甲基甲酰胺 为溶剂， 生成 [RuCl2((R)-5,5'-di(NHC(O)Ph)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)((R,R)-1,2-diphenylethylenediamine)]
  参考文献：
  名称：

  Dendritic BINAP based system for asymmetric hydrogenation of simple aryl ketones

  摘要：

  A series of dendritic BINAP-Ru/chiral diamine catalysts were developed for asymmetric hydrogenation of various simple aryl ketones. The resulting catalytic system showed very attractive due to very good catalytic activity and enantioselectivity as well as facile catalyst recycling. In the case of 1-acetonaphthone and 2'-methyl-acetophenone, interesting e.e. value up to 95% was observed which are comparable to the enantioselectivity reported by Noyori under similar conditions and higher than that of the heterogeneous poly(BINAP)-Ru catalyst reported by Pu and co-workers [Tetrahedron Lett. 41 (2000) 1681]. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s1381-1169(02)00452-1

文献信息

• Dendritic BINAP based system for asymmetric hydrogenation of simple aryl ketones
  作者：Guo-Jun Deng、Qing-Hua Fan、Xiao-Min Chen、Guo-Hua Liu

  DOI：10.1016/s1381-1169(02)00452-1

  日期：2003.2

  A series of dendritic BINAP-Ru/chiral diamine catalysts were developed for asymmetric hydrogenation of various simple aryl ketones. The resulting catalytic system showed very attractive due to very good catalytic activity and enantioselectivity as well as facile catalyst recycling. In the case of 1-acetonaphthone and 2'-methyl-acetophenone, interesting e.e. value up to 95% was observed which are comparable to the enantioselectivity reported by Noyori under similar conditions and higher than that of the heterogeneous poly(BINAP)-Ru catalyst reported by Pu and co-workers [Tetrahedron Lett. 41 (2000) 1681]. (C) 2002 Elsevier Science B.V. All rights reserved.