3-(but-1-enyl)pyridine | 90609-58-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-(but-1-enyl)pyridine
• 英文别名: 3-[(E)-but-1-enyl]pyridine
• CAS: 90609-58-8
• 化学式: C₉H₁₁N
• 分子量: 133.193
• InChiKey: KTXMSWAHSUYOHZ-HWKANZROSA-N

物化性质

• 沸点：
  209.2±9.0 °C(Predicted)
• 密度：
  0.950±0.06 g/cm3(Predicted)
• 保留指数：
  1176;1177;1145

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  diethylzinc 、 3-[(E)-2-硝基乙烯基]吡啶 以 乙醚 为溶剂， 反应 1.0h， 以36%的产率得到3-(but-1-enyl)pyridine
  参考文献：
  名称：

  Seebach, Dieter; Schaefer, Harald; Schmidt, Beat, Angewandte Chemie, 1992, vol. 104, # 12, p. 1680 - 1681

  摘要：

  DOI：

文献信息

• [EN] THERAPEUTIC COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS THÉRAPEUTIQUES ET LEURS UTILISATIONS
  申请人：GENENTECH INC

  公开号：WO2016055028A1

  公开（公告）日：2016-04-14

  The present invention relates to compounds of formula (I): and to salts thereof, wherein A has any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.

  本发明涉及式(I)的化合物及其盐，其中A具有规范中定义的任何值，以及其组合物和用途。这些化合物可用作CBP和/或EP300的抑制剂。还包括包含式(I)的化合物或其药学上可接受的盐的药物组合物，以及在治疗各种CBP和/或EP300介导的疾病中使用这些化合物和盐的方法。
• ALKOXYIMINO DERIVATIVE AND PEST CONTROL AGENT
  申请人：Fukumoto Shunichirou

  公开号：US20130102568A1

  公开（公告）日：2013-04-25

  [PROBLEMS] The present invention provides a novel alkoxyimino derivative or a salt thereof, as well as to a pest control agent containing the derivative or salt thereof as an active ingredient, which shows an excellent pest control effect on a wide range of pests in the agricultural and horticultural field and is also capable of controlling resistant pests. [MEANS FOR SOLVING PROBLEMS] The novel alkoxyimino derivative is characterized by being represented by general formula [I] (in the formula, X, R 1 , R 2 and Q are as defined in the specification) and the post control agent is characterized by containing as an active ingredient the alkoxyimino derivative or a salt thereof.

  本发明提供了一种新颖的烷氧基亚胺衍生物或其盐，以及一种含有该衍生物或其盐作为活性成分的杀虫剂，该杀虫剂对农业和园艺领域中广泛范围的害虫具有出色的杀虫效果，并且还能够控制抗性害虫。该新颖的烷氧基亚胺衍生物的特征在于其由通式[I]表示（在该式中，X、R1、R2和Q的定义如规范中所述），杀虫剂的特征在于其含有烷氧基亚胺衍生物或其盐作为活性成分。
• C-8 HALOGENATED MACROLIDES
  申请人：KIM IN JONG

  公开号：US20090209547A1

  公开（公告）日：2009-08-20

  The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

  本发明公开了具有以下结构的化合物（I）或其药用可接受的盐、酯或前药：该化合物具有抗菌性能。本发明还涉及包括上述化合物的药物组合物，用于治疗需要抗生素治疗的受试者。该发明还涉及通过给予包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。该发明还包括制备本发明化合物的方法。
• [EN] ARTHROPOD CONTROLLING COMPOSITION<br/>[FR] COMPOSITION DE LUTTE CONTRE LES ARTHROPODES
  申请人：FIRMENICH & CIE

  公开号：WO2020239980A1

  公开（公告）日：2020-12-03

  The present invention relates to an arthropod controlling composition comprising a compound according to formula (I), methods and uses to control arthropods as well as arthropod controlling articles comprising the same.

  本发明涉及一种包括根据式(I)的化合物的节肢动物控制组合物，以及用于控制节肢动物的方法和用途，以及包含相同化合物的节肢动物控制物品。
• NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
  申请人：Yoshida Tomohiro

  公开号：US20100228026A1

  公开（公告）日：2010-09-09

  The invention provides a sulfonyl malonamide derivative, or a pharmacologically acceptable salt thereof or a solvate thereof, that has therapeutic and/or preventive effect(s) on various diseases due to its agonist action at AT 2 receptor, and is useful as a pharmaceutical agent for the treatment and/or prevention of diseases involving the renin-angiotensin-aldosterone system (RAAS).

  该发明提供了一种磺酰基马隆酰胺衍生物，或其药理学上可接受的盐或溶剂，由于其在AT2受体上的激动剂作用，对各种疾病具有治疗和/或预防作用，并且作为用于治疗和/或预防涉及肾素-血管紧张素-醛固酮系统（RAAS）疾病的药物剂形具有用处。