1-[Pyrrolidin-1-ium-1-ylidene(pyrrolidin-1-yl)methoxy]benzotriazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: 1-[Pyrrolidin-1-ium-1-ylidene(pyrrolidin-1-yl)methoxy]benzotriazole
• 化学式: C15H20N5O+
• 分子量: 286.35
• InChiKey: WWLPQAXROLNWNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  46.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Process for preparing a cross-linked carboxyl polysaccharide and the cross-linked carboxyl polysaccharide
  申请人：Young Jenn-Jong

  公开号：US20050281855A1

  公开（公告）日：2005-12-22

  A process for preparing a cross-linked polysaccharide comprises providing a polysaccharide with free carboxyl and hydroxyl groups capable of forming an intermolecular ester bond and cross-linking the polysaccharide by using onium salt, phosphonium salt, uronium salt or carbenium salt and in the presence or in the absence of organic base as cross-link reagent to obtain a highly cross-linked polysaccharide. The cross-linked polysaccharide has high cross-linking density and is stable and slowly biodegradable.

  制备交联多糖的方法包括提供具有能够形成分子间酯键的自由羧基和羟基的多糖，并使用盐酸盐、磷酸盐、尿酸盐或碳酸盐作为交联试剂，同时存在或不存在有机碱，以获得高度交联的多糖。这种交联多糖具有高交联密度，稳定且缓慢生物降解。
• SYNTHESIS OF 4- (Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'- 2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE
  申请人：SCHERING CORPORATION

  公开号：EP1436284B1

  公开（公告）日：2005-08-03
• HYDANTOIN BASED KINASE INHIBITORS
  申请人：F.Hoffmann-La Roche AG

  公开号：EP1989186B1

  公开（公告）日：2010-11-17
• TRIZOL-1-OL ANALOGS ANTI-RETROVIRAL LATENCY DRUGS
  申请人：UNIVERSITY OF UTAH RESEARCH FOUNDATION

  公开号：US20160151365A1

  公开（公告）日：2016-06-02

  In one aspect, the invention relates to triazol-1-ol compounds, analogs thereof, compositions comprising same, and methods of using same, alone or in combination with other agents, to reactivate latent retroviruses, and more particularly to reactivate latent HIV-1. Such compounds, compositions, and methods can be used, for example, in connection with diagnosing and/or treating a retrovirus, and more specifically HIV-1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US7160901B2
  申请人：——

  公开号：US7160901B2

  公开（公告）日：2007-01-09