N-丙基乙酰苯胺 | 2437-98-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-丙基乙酰苯胺
• 中文别名: N-炳基乙酰苯胺
• 英文名称: N-propyl-acetanilide
• 英文别名: N-Propyl-acetanilid；Essigsaeure-propylanilid；N-phenyl-N-propyl-acetamide；N,N-n-Propylacetylanilin；N-n-Propylacetanilid；N-Propylacetanilide；N-phenyl-N-propylacetamide
• CAS: 2437-98-1
• 化学式: C₁₁H₁₅NO
• mdl: MFCD01671526
• 分子量: 177.246
• InChiKey: PREAZHGTUOIWRL-UHFFFAOYSA-N

物化性质

• 熔点：
  49°C
• 沸点：
  309.18°C (rough estimate)
• 密度：
  1.0290 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2924299090

反应信息

• 作为产物：
  描述：

  N-phenyl-N-(prop-2-ynyl)acetamide 在 乙醇 、 铂 作用下， 生成 N-丙基乙酰苯胺
  参考文献：
  名称：

  Wolf, Justus Liebigs Annalen der Chemie, 1952, vol. 576, p. 35,41

  摘要：

  DOI：

文献信息

• Ruthenium catalysed reduction of alkenes using sodium borohydride
  作者：Gareth R.A. Adair、Kamal K. Kapoor、Alexandre L.B. Scolan、Jonathan M.J. Williams

  DOI：10.1016/j.tetlet.2006.10.026

  日期：2006.12

  The reduction of alkenes has been achieved using NaBH4 as the reducing agent using 0.5–1.0 mol % Ru(PPh3)4H2 in the presence of water.

  使用NaBH 4作为还原剂，在水存在下，使用0.5–1.0 mol％Ru（PPh 3）4 H 2可以实现烯烃的还原。
• NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION
  申请人：Oshima Kunio

  公开号：US20120225866A1

  公开（公告）日：2012-09-06

  The present invention provides a novel diazepine compound that blocks the I Kur current or the Kv1.5 channel potently and more selectively than other K + channels. The present invention relates to a diazepine compound represented by General Formula (1) or a salt thereof, wherein R 1 , R 2 , R 3 , and R 4 are each independently hydrogen, lower alkyl, cyclo lower alkyl or lower alkoxy lower alkyl; R 2 and R 3 may be linked to form lower alkylene; A 1 is lower alkylene optionally substituted with one or more substituents selected from the group consisting of hydroxyl and oxo; Y 1 and Y 2 are each independently —N═ or —CH═; and R 5 is group represented by wherein R 6 and R 7 are each independently hydrogen or organic group; R 6 and R 7 may be linked to form a ring together with the neighboring group —X A —N—X B —; X A and X B are each independently a bond, lower alkylene, etc.

  本发明提供了一种新型的二氮杂环化合物，它可以有效地阻断IKur电流或Kv1.5通道，并比其他K+通道更具选择性。本发明涉及一种由通式（1）表示的二氮杂环化合物或其盐，其中R1、R2、R3和R4各自独立地表示氢、低碳基、环状低碳基或低烷氧基低碳基；R2和R3可以连接形成低碳烷基；A1是低碳烷基，可选地取代一个或多个羟基和氧代基；Y1和Y2各自独立地表示—N═或—CH═；R5是由下式表示的基：其中R6和R7各自独立地表示氢或有机基团；R6和R7可以与相邻的基团—XA—N—XB—一起形成环；XA和XB各自独立地表示键、低碳烷基等。
• Liquid-type transformerless thermal evaporating device
  申请人：EARTH CHEMICAL CO., LTD.

  公开号：EP0661907A2

  公开（公告）日：1995-07-05

  A device body is equipped with a heater unit (3) and a thermal evaporating agent (9) is filled in a tank (6), and a leading end of a core (8) for sucking up the thermal evaporating agent which is inserted is the tank (6) is inserted into the heater unit (3). The heater unit (3) is in an annular shape and is incorporated with a transformerless exothermic body (10). The transformerless exothermic body (10) is a positive temperature thermistor and the voltage-current characteristic thereof has a region, over the range of at least 100V to 240V of applied voltage, which satisfies the conditions ofVx + Iy = a (a is constant) in orthogonal coordinates in which a longitudinal axis is a voltage Vx and a lateral axis is a current Iy. Therefore, even though the applied voltages are 100 V and 240 V, the change of consumed current, P=VI is small and there causes no difference in their exothermic temperatures in the range of the applied voltages of 100 V to 240 V. Thus, even though the applied voltage is 100 V or 240 V, there causes no difference in consuming time of the thermal evaporating agent.

  设备本体装有一个加热器单元 (3)，热蒸发剂 (9) 填充在一个罐 (6) 中，用于吸起插入罐 (6) 的热蒸发剂的芯子 (8) 的前端插入加热器单元 (3)。加热器单元（3）呈环形，内装一个无变压器放热体（10）。无变压器放热体 (10) 是一个正温热敏电阻，其电压-电流特性在至少 100V 至 240V 的外加电压范围内有一个区域，满足正交坐标中 Vx + Iy = a（a 为常数）的条件，其中纵轴为电压 Vx，横轴为电流 Iy。因此，即使外加电压为 100 V 和 240 V，消耗电流 P=VI 的变化也很小，在 100 V 至 240 V 的外加电压范围内，它们的放热温度没有差别。
• Melatonergic agents
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP0706994A1

  公开（公告）日：1996-04-17

  New melatonergic agents are phenyl alkanyl or phenyl alkyl substituted carboxamides and ureas of Formula I: wherein: R₁ = C₁₋₃ alkyl, allyl, C₃₋₆ cycloalkyl substituted C₁₋₄ alkyl; R₂ = hydrogen, halogen or C₁₋₄ alkoxy; R₃ = hydrogen or C₁₋₄ alkyl; R₄ = C₁₋₄ alkyl, C₁₋₄ alkyl substituted amino, carboxylic acid substituted C₁₋₄ alkyl or C₃₋₆ cycloalkyl, C₁₋₄ alkoxy substituted C₁₋₄ alkyl, C₃₋₆ cycloalkyl, or straight or branched chain C₂₋₄ alkenyl; A = a linear C₂₋₄ alkanediyl or alkenediyl chain, provided that A not be -CH₂CH₂- when X is a bond; and X = a covalent bond or oxygen.

  新的褪黑激素制剂是式 I 的苯基烷基或苯基烷基取代的羧酰胺和脲： 其中 R₁ = C₁₋₃ 烷基、烯丙基、C₃₋₆ 环烷基取代的 C₁₋₄ 烷基； R₂ = 氢、卤素或 C₁₋₄ 烷氧基； R₃ = 氢或 C₁₋₄ 烷基； R₄ = C₁₋₄ 烷基、C₁₋₄ 烷基取代的氨基、羧酸取代的 C₁₋₄ 烷基或 C₃₋₆ 环烷基、C₁₋₄ 烷氧基取代的 C₁₋₄ 烷基、C₃₋₆ 环烷基或直链或支链 C₂₋₄ 烯基； A = 直链 C₂₋₄烷二基或烯二基，但当 X 为键时，A 不得为-CH₂CH₂-；以及 X = 共价键或氧。
• FAN TYPE CHEMICALS DIFFUSING DEVICE
  申请人：Fumakilla Limited

  公开号：EP1262100A1

  公开（公告）日：2002-12-04

  A fan type chemical diffusing apparatus is disclosed which comprises: an apparatus main body having an air inlet and an air outlet; a fan type blower disposed in the apparatus main body and having a fan casing, a fan provided with a hollow space, and a motor; and an active ingredient impregnated body or mass disposed in the hollow space for containing an active ingredient. The fan type blower is adapted and operative to send air from the air inlet through the hollow space into and out of the air outlet. A fan type debugging apparatus is also disclosed in which the active ingredient impregnated body or mass is disposed in a wind inlet side of the fan type blower and is designed to provide a wind force resistance which in terms of the proportion of current consumption by the motor in the presence of the active ingredient impregnated body or mass to current consumption by the motor in the absence of the active ingredient impregnated body or mass, ranges from 5 to 25 %. A fan type debugging apparatus is also disclosed in which a fan is used having: an air resistance f which when expressed by current consumption I1 by said motor loaded with said fan divided by current consumption I0 by the motor when unloaded with the fan, ranges not less than 1 but not greater than 17; the current consumption I0 being equal to or less than 35 mA; a size in a range between 20 mm and 100 mm in diameter; and a weight in a range between 1.5 gram and 8 grams, wherein values of the fan air resistance, size and weight are selected so that the current consumption by the motor loaded with the fan has a current value such that the ratio of a time period in which the fan can be driven by the battery to the capacity of the battery is not less than 5 %. A fan type debugging apparatus is also disclosed in which the fan type blower is operable to iteratively run and halt alternately with a time period of halt not more than 9 (nine) times as long as a running time period, the time period of halt being also a time period in which a current or quantity of electricity not lost therein is more than a current or quantity of electricity consumed in excess by the motor in the running time period.

  本发明公开了一种风扇式化学品扩散装置，该装置包括：具有进气口和出气口的装置主体；设置在装置主体中的风扇式鼓风机，该鼓风机具有风扇外壳、带有中空空间的风扇和电机；以及设置在中空空间中的活性成分浸渍体或块，该活性成分浸渍体或块含有活性成分。风扇型鼓风机适于并可用于将空气从进气口通过中空空间送入出气口。还公开了一种风扇型调试装置，其中活性成分浸渍体或块被放置在风扇型鼓风机的进风侧，并被设计为提供风力阻力，该风力阻力在有活性成分浸渍体或块存在时的电机电流消耗与无活性成分浸渍体或块存在时的电机电流消耗之间的比例为 5%至 25%。还公开了一种风扇型调试装置，其中使用的风扇具有：空气阻力 f，用所述风扇加载时的电机电流消耗量 I1 除以风扇空载时的电机电流消耗量 I0 表示，空气阻力 f 的范围不小于 1 但不大于 17；电流消耗量 I0 等于或小于 35 mA；尺寸范围为直径 20 毫米至 100 毫米；重量范围为 1.其中，风扇空气阻力、尺寸和重量的值的选择是为了使装载风扇的电机的电流消耗具有这样一个电流值，即电池可驱动风扇的时间段与电池容量之比不小于5%。还公开了一种风扇型调试装置，其中风扇型鼓风机可交替运行和停止，停止的时间段不超过运行时间段的 9（九）倍，停止的时间段也是其中未损耗的电流或电量大于电机在运行时间段中过量消耗的电流或电量的时间段。