4-(2-(4-Hydroxyphenyl)ethenyl)-1-methylpyridinium (protonated form) | 93627-17-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(2-(4-Hydroxyphenyl)ethenyl)-1-methylpyridinium (protonated form)
• 英文别名: 4-(4'-Hydroxystyryl)-N-methylpyridinium；4-[2-(1-methyl-1H-pyridin-1-ium-4-ylidene)ethylidene]cyclohexa-2,5-dien-1-one
• CAS: 93627-17-9
• 化学式: C₁₄H₁₄NO
• 分子量: 212.271
• InChiKey: DBOHWMPKJCJANT-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  24.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (E)-1-methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styryl)pyridin-1-ium iodide 在 亚硝酸氧盐 作用下， 以 二甲基亚砜 为溶剂， 生成 4-(2-(4-Hydroxyphenyl)ethenyl)-1-methylpyridinium (protonated form)
  参考文献：
  名称：

  Mitochondrial targeted fluorescent nitrite peroxide probe for dynamic monitoring of cellular lung injury

  摘要：

  DOI：

  10.1016/j.ab.2023.115114

文献信息

• TWISTED PI-ELECTRON SYSTEM CHROMOPHORE COMPOUNDS WITH VERY LARGE MOLECULAR HYPERPOLARIZABILITIES AND RELATED COMPOSITIONS AND DEVICES
  申请人：Marks Tobin J.

  公开号：US20100273919A1

  公开（公告）日：2010-10-28

  Unconventional twisted π-electron system electro-optic (EO) chromophores/compounds, compositions and related device structures. Crystallographic analysis of several non-limiting chromophores reveals, for instance, large ring-ring dihedral twist angles and a highly charge-separated zwitterionic structure in the ground state, in both solution phase and solid-state.

  非传统扭曲的π-电子体系电光（EO）色团/化合物，组成和相关器件结构。对几种非限制性色团的晶体学分析显示，例如在溶液相和固态中，存在大的环-环二面角扭转角和高度电荷分离的带电离子结构。
• METHODS TO INCREASE THE PHOTOSTABILITY OF DYES
  申请人：Hahn Klaus

  公开号：US20110046000A1

  公开（公告）日：2011-02-24

  The presently disclosed subject matter provides dyes having an improved photostability, biosensors comprising such dyes, and methods of use thereof, including methods for detecting target molecules in a sample under test and for live-cell imaging. The dyes can include a binding member, including a biomolecule or fragments thereof, which can interact with target molecules of interest and can be specific to a given conformational state or covalent modification, e.g., phosphorylation, of the target molecule. The presently disclosed dyes can be used for detecting changes in the binding, conformational change, or posttranslational modification of the target molecule.

  所述主题提供了具有改善光稳定性的染料、包括此类染料的生物传感器以及其使用方法，包括用于检测样品中的靶分子和用于活细胞成像的方法。该染料可以包括结合成员，包括生物分子或其片段，其可以与感兴趣的靶分子相互作用，并且可以特定于给定的构象状态或靶分子的共价修饰，例如磷酸化。目前披露的染料可用于检测靶分子的结合、构象变化或后翻译修饰的变化。
• Twisted Pi-Electron System Chromophore Compounds with Very Large Molecular Hyperpolarizabilities and Related Compositions and Devices
  申请人：Marks Tobin J.

  公开号：US20110278512A1

  公开（公告）日：2011-11-17

  Unconventional twisted π-electron system electro-optic (EO) chromophores/compounds, compositions and related device structures. Crystallographic analysis of several non-limiting chromophores reveals, for instance, large ring-ring dihedral twist angles and a highly charge-separated zwitterionic structure in the ground state, in both solution phase and solid-state.

  非传统的扭曲π电子体系的电光（EO）色团/化合物、组成和相关器件结构。对几种非限制性的色团进行晶体学分析，例如大的环-环二面角扭曲角度以及在溶液相和固态中均表现出高度带电离子结构的基态。
• 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM
  申请人：PerkinElmer LAS, Inc.

  公开号：EP1161555B1

  公开（公告）日：2008-01-02
• Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same
  申请人：Wilson James N.

  公开号：US20120294808A1

  公开（公告）日：2012-11-22

  A method of imaging using selective fluorescent emitters and compositions for imaging are described. The method can include contacting a specimen with a composition comprising at least one selective fluorescent emitter of Formulas I through IX and irradiating the specimen with an excitation wavelength. The fluorescence emitted by the selective fluorescent emitter can be detected to generate an image. Formulas I through IX are: wherein: R 1 =OR 4 or NR 3 R 4 ; R 2 =OR 4 , NR 3 R 4 , Cl, F or H; R 3 =H, CH 3 , C 2 H 5 , C 3 H 7 or C 4 H 9 ; R 4 =H, CH 3 , C 2 H 5 , C 3 H 7 or C 4 H 9 ; R 5 =H or CH 2 (CH 2 ) n NR 3 R 4 ; R 6 =H or CH 2 (CH 2 ) n NR 3 R 4 ; R 7 =OR 4 , NR 3 R 4 , Cl, F or H; R 8 =N-methylpyridinium or N-methyl-1,2,3,6-tetrahydropyridine; and n=1, 2 or 3.