2-(5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)-N-{(1S)-1-[(S)-(5-tert-butyl-1,3,4-oxadiazol-2-yl)(hydroxy)methyl]-2-methylpropyl}acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-(5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)-N-{(1S)-1-[(S)-(5-tert-butyl-1,3,4-oxadiazol-2-yl)(hydroxy)methyl]-2-methylpropyl}acetamide
• 英文别名: 2-(5-amino-6-oxo-2-phenylpyrimidin-1-yl)-N-[(1S,2S)-1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-1-hydroxy-3-methylbutan-2-yl]acetamide
• 化学式: C₂₃H₃₀N₆O₄
• 分子量: 454.5
• InChiKey: HMPQTEPEMQZWQH-ROUUACIJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  147
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• [EN] COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS AND METHOD OF TREATING CANCER<br/>[FR] COMPOSITIONS, PROCÉDÉ DE PRÉPARATION DE LADITE COMPOSITION ET MÉTHODE DE TRAITEMENT DU CANCER
  申请人：CELLWORKS RES INDIA PRIVATE LTD

  公开号：WO2013086002A1

  公开（公告）日：2013-06-13

  The present disclosure describes a composition and a kit having a combination of compounds for use in the treatment of cancer and associated conditions and therapies. The disclosure also relates to a process of obtaining the composition and the method of treating cancer and associated conditions by administration of the compositions.