5-(2-phenyl-3H-pyrazolo[1,5-a]pyridin-8-ium-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 5-(2-phenyl-3H-pyrazolo[1,5-a]pyridin-8-ium-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine
• 化学式: C18H14N7+
• 分子量: 328.4
• InChiKey: YKONQXIRPQFGOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  96.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Methods of diagnosing and treating autism spectrum disorders
  申请人：The Regents of the University of California

  公开号：US10941194B2

  公开（公告）日：2021-03-09

  The invention describes a method of diagnosing an individual as having an increased likelihood of having an autism spectrum disorder and in some instances, selecting a therapy. The invention is related to a system or a kit for performing such a method.

  本发明描述了一种诊断个人患自闭症谱系障碍可能性增加的方法，以及在某些情况下选择疗法的方法。本发明涉及一种用于执行这种方法的系统或套件。
• INHIBITORS OF ERK FOR DEVELOPMENTAL DISORDERS OF NEURONAL CONNECTIVITY
  申请人：Case Western Reserve University

  公开号：EP2600862A2

  公开（公告）日：2013-06-12
• METHODS OF DIAGNOSING AND TREATING AUTISM SPECTRUM DISORDERS
  申请人：The Regents of the University of California

  公开号：US20180002410A1

  公开（公告）日：2018-01-04

  The invention describes a method of diagnosing an individual as having an increased likelihood of having an autism spectrum disorder and in some instances, selecting a therapy. The invention is related to a system or a kit for performing such a method.
• [EN] INHIBITORS OF ERK FOR DEVELOPMENTAL DISORDERS OF NEURONAL CONNECTIVITY<br/>[FR] INHIBITEURS DE L'ERK DESTINÉS À TRAITER DES TROUBLES DU DÉVELOPPEMENT DE LA CONNECTIVITÉ NEURONALE
  申请人：UNIV CASE WESTERN RESERVE

  公开号：WO2012019113A2

  公开（公告）日：2012-02-09

  A method of treating a subject at risk of or suspected of having Fragile X syndrome or autism spectrum disorder associated with abnormalities of ERK includes administering to the subject a therapeutically effective amount of at least one ERK inhibiting compound that prevents abnormalities in neuronal connectivity, a prodrug thereof that is metabolisable to form the compound, or a pharmaceutically acceptable salt thereof.
• [EN] METHODS OF DIAGNOSING AND TREATING AUTISM SPECTRUM DISORDERS<br/>[FR] MÉTHODES DE DIAGNOSTIC ET DE TRAITEMENT DE TROUBLES DU SPECTRE AUTISTIQUE
  申请人：UNIV CALIFORNIA

  公开号：WO2016118924A1

  公开（公告）日：2016-07-28

  The invention describes a method of diagnosing an individual as having an increased likelihood of having an autism spectrum disorder and in some instances, selecting a therapy. The invention is related to a system or a kit for performing such a method.