The present invention discloses novel substituted aryl- and heteroarylphenyloxazolidinones which are useful as anti-bacterial agents. More specifically, the substituted aryl- and heteroarylphenyloxazolidinones of the invention are characterized by oxazolidinones having an aryl or heteroaryl group at the p-position of the 3-phenyl ring and additional substitutions at the m-position(s) of the 3-phenyl ring. A compound representative of this new class of oxazolidinones is (.+-.)-5-(acetamidomethyl)-3-\x9b4-(3-pyridyl)-3,5-difluorophenyl!-2-oxazolid inone.
本发明公开了一种新型的取代芳基和杂环芳基苯基
噁唑啉酮,其可用作抗菌剂。更具体地说,本发明的取代芳基和杂环芳基苯基
噁唑啉酮的特征在于在3-苯环的p-位置具有芳基或杂环芳基基团,并在3-苯环的m-位置具有额外的取代基。这种新型
噁唑啉
酮类化合物的代表是(.+-.)-5-(乙酰胺甲基)-3-\x9b4-(3-
吡啶基)-3,5-二
氟苯基!-2-
噁唑啉酮。