plaunol E | 69749-02-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: plaunol E
• 英文别名: [(1S)-2-[(1R,2S,4S,9R,12S,13R)-4,13-dihydroxy-11-methylidene-7-oxo-8,14-dioxatetracyclo[7.6.0.01,6.02,12]pentadec-5-en-12-yl]-1-(furan-3-yl)ethyl] acetate
• CAS: 69749-02-6
• 化学式: C₂₂H₂₄O₈
• 分子量: 416.428
• InChiKey: CRUGKFQBOCUEHC-IYROKSPBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  115
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 plaunol E 以 吡啶 为溶剂， 以19 mg的产率得到
  参考文献：
  名称：

  Novel diterpenelactones with anti-peptic ulcer activity from Croton sublyratus.

  摘要：

  Five novel furanoditerpenes of the ent-clerodane type, plaunol A (1), B (2), C (3), D (4) and E (5), were isolated from a fraction of Croton sublyratus KURZ extract with potent anti-Shay ulcer activity. Their absolute structures were determined from the spectral data and by chemical correlations.

  DOI：

  10.1248/cpb.28.227

文献信息

• Novel diterpenelactones with anti-peptic ulcer activity from Croton sublyratus.
  作者：EIICHI KITAZAWA、AIYA SATO、SHUJI TAKAHASHI、HARUMITSU KUWANO、AKIRA OGISO

  DOI：10.1248/cpb.28.227

  日期：——

  Five novel furanoditerpenes of the ent-clerodane type, plaunol A (1), B (2), C (3), D (4) and E (5), were isolated from a fraction of Croton sublyratus KURZ extract with potent anti-Shay ulcer activity. Their absolute structures were determined from the spectral data and by chemical correlations.