3-Bromo-4-(2-bromo-phenylsulfanyl)-tetrahydro-thiophene 1,1-dioxide | 210908-39-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3-Bromo-4-(2-bromo-phenylsulfanyl)-tetrahydro-thiophene 1,1-dioxide
• 英文别名: 3-Bromo-4-(2-bromophenyl)sulfanylthiolane 1,1-dioxide
• CAS: 210908-39-7
• 化学式: C₁₀H₁₀Br₂O₂S₂
• 分子量: 386.128
• InChiKey: UURNVNOVVYFFGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  67.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-Bromo-4-(2-bromo-phenylsulfanyl)-tetrahydro-thiophene 1,1-dioxide 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 72.0h， 以91%的产率得到3-[(2-Bromophenyl)sulfanyl]-2,3-dihydro-1H-1lambda~6~-thiophene-1,1-dione
  参考文献：
  名称：

  Preparation and Reactions of Benzofurano-, Indolo-, and Benzothieno-3-sulfolenes

  摘要：

  Benzofurano-, N-tosylindolo-, and benzothieno-3-sulfolenes have been prepared efficiently via their dihydro analogues. These fused 3-sulfolenes serve as ideal precursors for the corresponding heteroaromatic o-quinodimethanes. Derivatives of these 3-sulfolenes bearing bromo or alkyl group substitution from which substituted heteroaromatic o-quinodimethanes are generated have also been synthesized.

  DOI：

  10.1021/jo980044e
• 作为产物：
  描述：

  3-环丁烯砜 、 2-溴硫代苯酚 在 N-溴代丁二酰亚胺(NBS) 作用下， 生成 3-Bromo-4-(2-bromo-phenylsulfanyl)-tetrahydro-thiophene 1,1-dioxide
  参考文献：
  名称：

  Preparation and Reactions of Benzofurano-, Indolo-, and Benzothieno-3-sulfolenes

  摘要：

  Benzofurano-, N-tosylindolo-, and benzothieno-3-sulfolenes have been prepared efficiently via their dihydro analogues. These fused 3-sulfolenes serve as ideal precursors for the corresponding heteroaromatic o-quinodimethanes. Derivatives of these 3-sulfolenes bearing bromo or alkyl group substitution from which substituted heteroaromatic o-quinodimethanes are generated have also been synthesized.

  DOI：

  10.1021/jo980044e

文献信息

• Preparation and Reactions of Benzofurano-, Indolo-, and Benzothieno-3-sulfolenes
  作者：Chung-Wen Ko、Ta-shue Chou

  DOI：10.1021/jo980044e

  日期：1998.7.1

  Benzofurano-, N-tosylindolo-, and benzothieno-3-sulfolenes have been prepared efficiently via their dihydro analogues. These fused 3-sulfolenes serve as ideal precursors for the corresponding heteroaromatic o-quinodimethanes. Derivatives of these 3-sulfolenes bearing bromo or alkyl group substitution from which substituted heteroaromatic o-quinodimethanes are generated have also been synthesized.