1-ethylsulfanyl-2,2-dimethyl-propane | 57093-96-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1-ethylsulfanyl-2,2-dimethyl-propane
• 英文别名: 1-Ethylsulfanyl-2,2-dimethylpropane
• CAS: 57093-96-6
• 化学式: C₇H₁₆S
• 分子量: 132.27
• InChiKey: HWSIHEGMHQIQAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  methyl dithiopivalate 、 乙基溴化镁 生成 1-ethylsulfanyl-2,2-dimethyl-propane
  参考文献：
  名称：

  Leger,L.; Saquet,M., Bulletin de la Societe Chimique de France, 1975, p. 657 - 666

  摘要：

  DOI：

文献信息

• PHENYL BICYCLIC METHYL AZETIDINE DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS
  申请人：Takeuchi Janet A.

  公开号：US20120264732A1

  公开（公告）日：2012-10-18

  The present invention relates to novel phenyl bicyclic methyl azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.

  本发明涉及新型苯基双环甲基氮杂环丙烷衍生物，其制备方法，含有它们的药物组合物以及它们作为调节鞘氨醇-1-磷酸受体的药物的用途。
• SUBSTITUTED BICYCLIC METHYL AMINE DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS
  申请人：Takeuchi Janet A.

  公开号：US20120264715A1

  公开（公告）日：2012-10-18

  The present invention relates to novel substituted bicyclic methyl amine derivatives which are useful as sphingosine-1-phosphate receptors modulators and useful for treating a wide variety of disorders associated with modulation of sphingosine-1-phosphate receptors.

  本发明涉及一种新型的取代双环甲基胺衍生物，其可用作鞘氨醇-1-磷酸受体调节剂，并可用于治疗与鞘氨醇-1-磷酸受体调节相关的各种疾病。
• Molecular constructs suitable for targeted conjugates
  申请人：Henri John T.

  公开号：US20090246211A1

  公开（公告）日：2009-10-01

  The present invention relates generally to effective drug-linker constructs suitable for conjugation with ligands. The present invention also discloses methods of conjugating these constructs with peptides to form the compound of formula I. These methods are readily extended to any hydroxyl, amine or sulfur bearing biologically active molecules. B—X—L 1 —(L 2 ) m —(L 3 ) n —Y—RL  I

  本发明涉及一般适用于与配体结合的有效药物-连接物构造。本发明还揭示了将这些构造物与肽共轭形成式I化合物的方法。这些方法可轻松扩展到任何具有羟基、胺基或硫基的生物活性分子。B-X-L1-(L2)m-(L3)n-Y-R L  I。
• COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING COLOR FILTER, SOLID-STATE IMAGE SENSOR AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：KANNA Shinichi

  公开号：US20110217636A1

  公开（公告）日：2011-09-08

  The present invention provides a colored curable composition including a phthalocyanine pigment, a dioxazine pigment, a dye, a polymerization initiator, a polymerizable compound and a solvent; and a colored curable composition including a phthalocyanine pigment, a dye multimer having a polymerizable group and a group derived from a dipyrromethene dye, a polymerization initiator, a polymerizable compound and a solvent.

  本发明提供了一种彩色可固化组合物，包括酞菁颜料、二氧化锰颜料、染料、聚合引发剂、可聚合化合物和溶剂；以及一种彩色可固化组合物，包括酞菁颜料、具有可聚合基团和源自二吡咯甲烷染料的染料多聚物、聚合引发剂、可聚合化合物和溶剂。
• INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING LFA-1
  申请人：Hoffmann-La Roche Inc.

  公开号：US20150065534A1

  公开（公告）日：2015-03-05

  The invention relates to compounds of formula (I), wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to LFA-1 integrin antagonists to target cells expressing LFA-1.

  本发明涉及公式（I）的化合物，其中R1，R2和n在详细说明和权利要求中有定义。特别是，本发明涉及公式I的化合物，用于制造和传递共轭基团，如小分子、肽、核酸、荧光基团和聚合物，这些共轭基团与LFA-1整合素拮抗剂连接，以靶向表达LFA-1的细胞。