CYCLOBUTYL PURINE DERIVATIVE, ANGIOGENESIS PROMOTING AGENT, LUMENIZATION PROMOTING AGENT, NEUROCYTE GROWTH PROMOTING AGENT, AND DRUG
申请人:National University Corporation Kagawa University
公开号:EP2377865A1
公开(公告)日:2011-10-19
Provided is a compound having at least one selected from the group consisting of cell growth promoting activity, angiogenesis promoting activity, lumen formation promoting activity, cell migration promoting activity, and neurocyte growth promoting activity, which is a chemically stable low-molecular-weight substance that has high absorbability and can be supplied stably at a low cost because of its low molecular weight. A cyclobutyl purine derivative, a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof according to the present invention is a cyclobutyl purine derivative represented by the following general formula (1), a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof.
本发明提供了一种化合物,该化合物具有至少一种选自细胞生长促进活性、血管生成促进活性、管腔形成促进活性、细胞迁移促进活性和神经细胞生长促进活性组成的组的活性,它是一种化学性质稳定的低分子量物质,具有高吸收性,并且由于其分子量低,可以以较低的成本稳定供应。根据本发明的环丁基嘌呤衍生物、其同分异构体或立体异构体,或其盐、溶液或水合物是由以下通式(1)表示的环丁基嘌呤衍生物、其同分异构体或立体异构体,或其盐、溶液或水合物。