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    —— 8-cyclohexyl-6-[3-methyl-4-(thiophene-3-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C25H30N4O2S
    8-cyclohexyl-6-[3-methyl-4-(thiophene-3-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-((3R)-3-isopropyl-4-(2-(tetrahydrofuran-3-yloxy)acetyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416270-01-3 C27H38N4O4
    8-cyclopropyl-6-((3R)-3-isopropyl-4-(2-(tetrahydrofuran-3-yloxy)acetyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-56-9 C24H28N4O3
    8-cyclohexyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-[3-methyl-4-(2-methylfuran-3-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C26H32N4O3
    8-cyclohexyl-6-[3-methyl-4-(2-methylfuran-3-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-3,3-dimethyl-6-[3-propan-2-yl-4-(2-propoxyacetyl)piperazin-1-yl]-1,4-dihydroisochromene-5-carbonitrile —— C27H39N3O3
    8-Cyclopropyl-3,3-dimethyl-6-[3-propan-2-yl-4-(2-propoxyacetyl)piperazin-1-yl]-1,4-dihydroisochromene-5-carbonitrile
    —— 8-Cyclopropyl-3,3-dimethyl-6-[3-propan-2-yl-4-(2-pyridin-3-yloxyacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C28H35N5O3
    8-Cyclopropyl-3,3-dimethyl-6-[3-propan-2-yl-4-(2-pyridin-3-yloxyacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-[(3R)-4-(2-ethoxyacetyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydroisochromene-5-carbonitrile —— C26H37N3O3
    8-cyclopropyl-6-[(3R)-4-(2-ethoxyacetyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydroisochromene-5-carbonitrile
    —— 8-Cyclopropyl-6-[3-ethyl-4-(2-methylfuran-3-carbonyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C26H32N4O3
    8-Cyclopropyl-6-[3-ethyl-4-(2-methylfuran-3-carbonyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclobutyl-6-[4-(3-methoxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C26H38N4O3
    8-Cyclobutyl-6-[4-(3-methoxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(3-ethyl-4-(furan-2-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416266-85-7 C26H32N4O3
    8-cyclohexyl-6-(3-ethyl-4-(furan-2-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-3,3-dimethyl-6-[3-propan-2-yl-4-[2-(triazol-2-yl)acetyl]piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C25H33N7O2
    8-Cyclopropyl-3,3-dimethyl-6-[3-propan-2-yl-4-[2-(triazol-2-yl)acetyl]piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-((2S,5R)-4-(3-methoxypropanoyl)-2,5-dimethylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416268-94-4 C24H34N4O3
    8-cyclopropyl-6-((2S,5R)-4-(3-methoxypropanoyl)-2,5-dimethylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-[3-methyl-4-(thiophene-2-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C25H30N4O2S
    8-cyclohexyl-6-[3-methyl-4-(thiophene-2-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-[4-(imidazo[1,2-a]pyridine-3-carbonyl)-3-methylpiperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C28H32N6O2
    8-cyclohexyl-6-[4-(imidazo[1,2-a]pyridine-3-carbonyl)-3-methylpiperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-3,3-dimethyl-6-[4-[2-(4-methylpyrazol-1-yl)acetyl]-3-propan-2-ylpiperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C27H36N6O2
    8-Cyclopropyl-3,3-dimethyl-6-[4-[2-(4-methylpyrazol-1-yl)acetyl]-3-propan-2-ylpiperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclohexyl-3,3-dimethyl-6-[3-methyl-4-(2-phenylacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C30H38N4O2
    8-Cyclohexyl-3,3-dimethyl-6-[3-methyl-4-(2-phenylacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-6-[3-ethyl-4-(1,3-thiazole-4-carbonyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydroisochromene-5-carbonitrile —— C25H30N4O2S
    8-Cyclopropyl-6-[3-ethyl-4-(1,3-thiazole-4-carbonyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydroisochromene-5-carbonitrile
    —— 8-cyclopropyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-94-5 C23H26N4O3
    8-cyclopropyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-6-(4-ethylsulfonyl-3-propan-2-ylpiperazin-1-yl)-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C23H34N4O3S
    8-Cyclopropyl-6-(4-ethylsulfonyl-3-propan-2-ylpiperazin-1-yl)-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-(4-(furan-3-carbonyl)-3,3-dimethylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416269-02-7 C25H30N4O3
    8-cyclopropyl-6-(4-(furan-3-carbonyl)-3,3-dimethylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-68-3 C26H32N4O3
    8-cyclohexyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-(Cyclobutadienyl)-3,3-dimethyl-6-[3-propan-2-yl-4-(2-thiophen-2-ylacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C28H32N4O2S
    8-(Cyclobutadienyl)-3,3-dimethyl-6-[3-propan-2-yl-4-(2-thiophen-2-ylacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-6-[4-(2-indol-1-ylacetyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C31H37N5O2
    8-Cyclopropyl-6-[4-(2-indol-1-ylacetyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-3,3-dimethyl-6-(4-methylsulfonyl-3-propan-2-ylpiperazin-1-yl)-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C22H32N4O3S
    8-Cyclopropyl-3,3-dimethyl-6-(4-methylsulfonyl-3-propan-2-ylpiperazin-1-yl)-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(furan-3-carbonyl)-3-phenylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-95-6 C32H36N4O3
    8-cyclohexyl-6-(4-(furan-3-carbonyl)-3-phenylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-[3-methyl-4-(3-methylfuran-2-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C26H32N4O3
    8-cyclohexyl-6-[3-methyl-4-(3-methylfuran-2-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclobutyl-3,3-dimethyl-6-[3-propan-2-yl-4-(2-thiophen-2-ylacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C28H36N4O2S
    8-Cyclobutyl-3,3-dimethyl-6-[3-propan-2-yl-4-(2-thiophen-2-ylacetyl)piperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-6-[3-ethyl-4-(2-pyridin-3-ylacetyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydroisochromene-5-carbonitrile —— C28H34N4O2
    8-Cyclopropyl-6-[3-ethyl-4-(2-pyridin-3-ylacetyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydroisochromene-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(furan-3-carbonyl)-3-methylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416266-75-5 C27H34N4O3
    8-cyclohexyl-6-(4-(furan-3-carbonyl)-3-methylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-(Cyclobutadienyl)-6-[4-(furan-3-carbonyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C27H30N4O3
    8-(Cyclobutadienyl)-6-[4-(furan-3-carbonyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-(4-(furan-2-carbonyl)-3,3-dimethylpiperazin-1-yl)-3,3-dimethylisochroman-5-carbonitrile —— C26H31N3O3
    8-cyclopropyl-6-(4-(furan-2-carbonyl)-3,3-dimethylpiperazin-1-yl)-3,3-dimethylisochroman-5-carbonitrile
    —— 8-cyclopropyl-6-((2S,5R)-4-(furan-3-carbonyl)-2,5-dimethylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416268-92-2 C25H30N4O3
    8-cyclopropyl-6-((2S,5R)-4-(furan-3-carbonyl)-2,5-dimethylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-isopropyl-3,3-dimethyl-6-(4-(2-methylfuran-3-carbonyl)-2-phenylpiperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416266-97-1 C30H34N4O3
    8-isopropyl-3,3-dimethyl-6-(4-(2-methylfuran-3-carbonyl)-2-phenylpiperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-3,3-dimethyl-6-[4-[2-(3-methylpyrazol-1-yl)acetyl]-3-propan-2-ylpiperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C27H36N6O2
    8-Cyclopropyl-3,3-dimethyl-6-[4-[2-(3-methylpyrazol-1-yl)acetyl]-3-propan-2-ylpiperazin-1-yl]-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-(4-(furan-2-carbonyl)-3-methylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-87-6 C24H28N4O3
    8-cyclopropyl-6-(4-(furan-2-carbonyl)-3-methylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-[(3R)-3-methyl-4-(thiophene-2-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C25H30N4O2S
    8-cyclohexyl-6-[(3R)-3-methyl-4-(thiophene-2-carbonyl)piperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopentyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-76-3 C23H26N4O3
    8-cyclopentyl-6-(4-(furan-2-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-(3-fluorophenyl)-6-(4-(furan-3-carbonyl)-3-methylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-82-1 C27H27FN4O3
    8-(3-fluorophenyl)-6-(4-(furan-3-carbonyl)-3-methylpiperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(furan-2-carbonyl)-3-methylpiperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-84-3 C25H30N4O3
    8-cyclohexyl-6-(4-(furan-2-carbonyl)-3-methylpiperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(2,5-dimethylfuran-3-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-73-0 C26H32N4O3
    8-cyclohexyl-6-(4-(2,5-dimethylfuran-3-carbonyl)piperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-hydroxy-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416271-00-5 C17H22N2O2
    8-cyclohexyl-6-hydroxy-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclopropyl-6-[4-(furan-3-carbonyl)-3-phenylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C29H30N4O3
    8-Cyclopropyl-6-[4-(furan-3-carbonyl)-3-phenylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-ethoxy-N-(4-methoxyphenyl)-4,4-dimethyl-5H-dithiolo[3,4-c]quinolin-1-imine —— C21H22N2O2S2
    8-ethoxy-N-(4-methoxyphenyl)-4,4-dimethyl-5H-dithiolo[3,4-c]quinolin-1-imine
    —— 8-Cyclopropyl-6-[4-(furan-2-carbonyl)-2-methylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C24H28N4O3
    8-Cyclopropyl-6-[4-(furan-2-carbonyl)-2-methylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-(3-(methoxymethyl)-4-(3-methoxypropanoyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416269-87-8 C24H34N4O4
    8-cyclopropyl-6-(3-(methoxymethyl)-4-(3-methoxypropanoyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-[4-(furan-2-carbonyl)-2-methylpiperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile —— C25H30N4O3
    8-cyclohexyl-6-[4-(furan-2-carbonyl)-2-methylpiperazin-1-yl]-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclobutyl-6-[4-(furan-3-carbonyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C27H34N4O3
    8-Cyclobutyl-6-[4-(furan-3-carbonyl)-3-propan-2-ylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclohexyl-6-(4-(furan-3-carbonyl)-3-methylpiperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile 1416265-85-4 C25H30N4O3
    8-cyclohexyl-6-(4-(furan-3-carbonyl)-3-methylpiperazin-1-yl)-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-Cyclohexyl-6-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile —— C26H38N4O3
    8-Cyclohexyl-6-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile
    —— 8-cyclopropyl-6-(4-(furan-3-carbonyl)-3-phenylpiperazin-1-yl)-3,3-dimethylisochroman-5-carbonitrile —— C30H31N3O3
    8-cyclopropyl-6-(4-(furan-3-carbonyl)-3-phenylpiperazin-1-yl)-3,3-dimethylisochroman-5-carbonitrile