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    —— 8-[[[(1R)-2-methyl-1-[1-(2-phenylethyl)tetrazol-5-yl]propyl]-(thiophen-2-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H32N6O3S
    8-[[[(1R)-2-methyl-1-[1-(2-phenylethyl)tetrazol-5-yl]propyl]-(thiophen-2-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[cyclopentyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)-2-methylpropyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C27H36N6O3
    8-[[cyclopentyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)-2-methylpropyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-(1-tert-butyltetrazol-5-yl)-2-methylpropyl]-(2-hydroxyethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C23H32N6O4
    8-[[[(1R)-1-(1-tert-butyltetrazol-5-yl)-2-methylpropyl]-(2-hydroxyethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1S)-1-(1-tert-butyltetrazol-5-yl)-2-methylpropyl]-(2-hydroxyethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C23H32N6O4
    8-[[[(1S)-1-(1-tert-butyltetrazol-5-yl)-2-methylpropyl]-(2-hydroxyethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-(1-tert-butyltetrazol-5-yl)-2-methylpropyl]-[(4-fluorophenyl)methyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C28H33FN6O3
    8-[[[(1R)-1-(1-tert-butyltetrazol-5-yl)-2-methylpropyl]-[(4-fluorophenyl)methyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-Methoxy-3-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazine-1-carbonyl]chromen-2-one —— C26H26N4O4S
    8-Methoxy-3-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazine-1-carbonyl]chromen-2-one
    —— 8-Benzyl-3-benzylsulfanyl-7-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine —— C20H19N5S
    8-Benzyl-3-benzylsulfanyl-7-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
    —— 8-Benzyl-3-[(4-methoxyphenyl)methylsulfanyl]-7-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine —— C21H21N5OS
    8-Benzyl-3-[(4-methoxyphenyl)methylsulfanyl]-7-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
    —— 8-(4-Morpholin-4-ylsulfonylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane —— C17H24N2O7S2
    8-(4-Morpholin-4-ylsulfonylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
    —— 8-[4-[(3R)-3-methylpiperidin-1-yl]sulfonylphenyl]sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane —— C19H28N2O6S2
    8-[4-[(3R)-3-methylpiperidin-1-yl]sulfonylphenyl]sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
    —— 8-[4-(4-Methyl-piperidine-1-sulfonyl)-benzenesulfonyl]-1,4-dioxa-8-aza-spiro[4.5]decane —— C19H28N2O6S2
    8-[4-(4-Methyl-piperidine-1-sulfonyl)-benzenesulfonyl]-1,4-dioxa-8-aza-spiro[4.5]decane
    —— 8-[4-(Azepan-1-ylsulfonyl)phenyl]sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane —— C19H28N2O6S2
    8-[4-(Azepan-1-ylsulfonyl)phenyl]sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
    —— 8-(4-Pyrrolidin-1-ylsulfonylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane —— C17H24N2O6S2
    8-(4-Pyrrolidin-1-ylsulfonylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
    —— 8-methyl-3-[8-methyl-3-[[(2S)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one —— C23H24N4O2
    8-methyl-3-[8-methyl-3-[[(2S)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one
    —— 8-methyl-3-[7-methyl-3-(2-phenylethylamino)imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one —— C26H24N4O
    8-methyl-3-[7-methyl-3-(2-phenylethylamino)imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one
    —— 8-methyl-3-[8-methyl-3-[[(2R)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one —— C23H24N4O2
    8-methyl-3-[8-methyl-3-[[(2R)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one
    —— 8-methyl-3-[7-methyl-3-(2-methylbutan-2-ylamino)imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one —— C23H26N4O
    8-methyl-3-[7-methyl-3-(2-methylbutan-2-ylamino)imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one
    —— 8-methyl-3-[5-methyl-3-[[(2R)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one —— C23H24N4O2
    8-methyl-3-[5-methyl-3-[[(2R)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one
    —— 8-methyl-3-[5-methyl-3-[[(2S)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one —— C23H24N4O2
    8-methyl-3-[5-methyl-3-[[(2S)-oxolan-2-yl]methylamino]imidazo[1,2-a]pyridin-2-yl]-1H-quinolin-2-one
    —— (8aR)-2-[(1-tert-butyltetrazol-5-yl)methyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine —— C13H24N6
    (8aR)-2-[(1-tert-butyltetrazol-5-yl)methyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine
    —— (8aR)-2-[(R)-(1-cyclohexyltetrazol-5-yl)-(4-methylphenyl)methyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine —— C22H32N6
    (8aR)-2-[(R)-(1-cyclohexyltetrazol-5-yl)-(4-methylphenyl)methyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine
    —— (8aR)-2-[(S)-(4-fluorophenyl)-[1-(2-methylbutan-2-yl)tetrazol-5-yl]methyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine —— C20H29FN6
    (8aR)-2-[(S)-(4-fluorophenyl)-[1-(2-methylbutan-2-yl)tetrazol-5-yl]methyl]-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine
    —— 8-Methyl-1-(pyridin-3-ylmethylsulfanyl)-11-thia-2,4,10-triaza-benzo[b]fluorene —— C20H14N4S2
    8-Methyl-1-(pyridin-3-ylmethylsulfanyl)-11-thia-2,4,10-triaza-benzo[b]fluorene
    —— 8-[[cyclohexyl-[(1S)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H36N6O4
    8-[[cyclohexyl-[(1S)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[cyclopentyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C26H34N6O3
    8-[[cyclopentyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[1,3-benzodioxol-5-ylmethyl-[(1S)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H32N6O5
    8-[[1,3-benzodioxol-5-ylmethyl-[(1S)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[benzyl-[(1R)-1-(1-benzyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H30N6O3
    8-[[benzyl-[(1R)-1-(1-benzyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-cyclohexylamino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H34N6O3
    8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-cyclohexylamino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[cyclopentyl-[(1S)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C26H34N6O3
    8-[[cyclopentyl-[(1S)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[cyclopentyl-[(1S)-1-[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C26H34N6O4
    8-[[cyclopentyl-[(1S)-1-[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H29N7O3
    8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[1,3-benzodioxol-5-ylmethyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H32N6O5
    8-[[1,3-benzodioxol-5-ylmethyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[cyclohexyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C27H36N6O3
    8-[[cyclohexyl-[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]methyl-(2-phenylethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H30N6O4
    8-[[[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]methyl-(2-phenylethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— (8aR)-2-[3-methoxy-4-(tetrazol-1-yl)phenyl]sulfonyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine —— C15H20N6O3S
    (8aR)-2-[3-methoxy-4-(tetrazol-1-yl)phenyl]sulfonyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine
    —— 8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-[(4-fluorophenyl)methyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H29FN6O3
    8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-[(4-fluorophenyl)methyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1S)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H31N7O4
    8-[[[(1S)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-(thiophen-2-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C28H28N6O3S
    8-[[[(1R)-1-(1-benzyltetrazol-5-yl)propyl]-(thiophen-2-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H31N7O4
    8-[[[(1R)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-cyclohexylamino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H34N6O3
    8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-cyclohexylamino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-[(4-fluorophenyl)methyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H29FN6O3
    8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-[(4-fluorophenyl)methyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[furan-2-ylmethyl-[(1R)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H30N6O5
    8-[[furan-2-ylmethyl-[(1R)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C27H31N7O3
    8-[[[(1R)-1-(1-cyclopentyltetrazol-5-yl)propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[cyclohexyl-[(1R)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H36N6O4
    8-[[cyclohexyl-[(1R)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[benzyl-[(1S)-1-(1-benzyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C30H30N6O3
    8-[[benzyl-[(1S)-1-(1-benzyltetrazol-5-yl)propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-(thiophen-2-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C28H28N6O3S
    8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-(thiophen-2-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— 8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H29N7O3
    8-[[[(1S)-1-(1-benzyltetrazol-5-yl)propyl]-(pyridin-3-ylmethyl)amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— (8aR)-2-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]sulfonyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine —— C19H29N3O4S2
    (8aR)-2-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]sulfonyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine
    —— 8-[[furan-2-ylmethyl-[(1S)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one —— C29H30N6O5
    8-[[furan-2-ylmethyl-[(1S)-1-[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]propyl]amino]methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one
    —— (8aR)-2-[4-[(2R)-2-ethylpiperidin-1-yl]sulfonylphenyl]sulfonyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine —— C20H31N3O4S2
    (8aR)-2-[4-[(2R)-2-ethylpiperidin-1-yl]sulfonylphenyl]sulfonyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine