| 1515861-47-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• CAS: 1515861-47-8
• 化学式: C₁₀H₁₂N₄O₆
• 分子量: 284.228
• InChiKey: UONDXLCCSUPFGM-QPPQHZFASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.25
• 重原子数：
  20.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  172.42
• 氢给体数：
  6.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  D-葡糖醛酮 、 5,6-二氨基嘧啶-2,4-二醇 在 2-巯基乙醇 作用下， 以 水 为溶剂， 反应 1.0h， 生成
  参考文献：
  名称：

  Evaluation of Liquid Chromatographic Behavior of Lumazinic Derivatives, from α-Dicarbonyl Compounds, in Different C18 Columns: Application to Wine Samples Using a Fused-Core Column and Fluorescence Detection

  摘要：

  Several C18 columns, packed with totally porous particles of different sizes and shell thicknesses, have been compared for simultaneous determination of alpha-dicarbonyl compounds, previous derivatization to lumazinic derivatives. Chromatographic conditions for the separation have been optimized for each column, and chromatographic parameters have been calculated and exhaustively compared. A core-shell C18 column provided the best results, and a HPLC method with fluorimetric detection has been proposed. The developed method has been validated in terms of linearity, precision, and sensitivity. Detection and quantification limits obtained were comprised between 0.02 and 0.30 and 0.07 and 1.0 ng mL(-1) respectively, while RSD values obtained were lower than 6% and 5% in intraday and interday repeatability studies, respectively. The method has been applied to analysis of the alpha-dicarbonyl compounds in different types of wines. The higher levels of the total alpha-dicarbonyl compounds were found in sweet wines and the lower levels in white wines.

  DOI：

  10.1021/jf404180t

文献信息

• Bertho; Bentler, Justus Liebigs Annalen der Chemie, 1950, vol. 570, p. 130,134,135
  作者：Bertho、Bentler

  DOI：——

  日期：——