(1R,4R,7R,10R)-10-methyl-4-[(methyl(phenyl)amino)methyl]-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-1,2,3,4,7,8,9,10-octahydro-naphthalen-7-ol | 1224700-88-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (1R,4R,7R,10R)-10-methyl-4-[(methyl(phenyl)amino)methyl]-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-1,2,3,4,7,8,9,10-octahydro-naphthalen-7-ol
• CAS: 1224700-88-2
• 化学式: C₂₈H₄₇NO₂Si
• 分子量: 457.772
• InChiKey: DXOCPZRAXNQFKO-CEYYOHNYSA-N

反应信息

• 作为产物：
  描述：

  (1S,8aR)-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-1,2,3,4,8,8a-hexahydro-6(7H)-naphthalenone 、 异丙基氯化镁 在 cerium(III) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 生成 (1R,4R,7R,10R)-10-methyl-4-[(methyl(phenyl)amino)methyl]-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-1,2,3,4,7,8,9,10-octahydro-naphthalen-7-ol 、 (1R,4R,7S,10R)-10-methyl-4-[(methyl(phenyl)amino)methyl]-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-1,2,3,4,7,8,9,10-octahydro-naphthalen-7-ol
  参考文献：
  名称：

  First total synthesis of (+)-Carainterol A

  摘要：

  The first, stereospecific, and elegant synthesis of the natural product (+)-Carainterol A was developed by using the Robinson annulation reaction as a key step to build the eudesmane skeleton. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.02.001