| 163661-22-1

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - （3'->5'）-二核苷酸和类似物
• CAS: 163661-22-1
• 化学式: C₁₉H₂₅N₈O₈PS
• 分子量: 556.496
• InChiKey: GAGWZDLWQROLND-RJAKUFNQSA-N

反应信息

• 作为产物：
  描述：

  在 ammonium hydroxide 作用下， 以 水 、 乙腈 为溶剂， 反应 12.0h， 生成 、
  参考文献：
  名称：

  Studies of Asymmetric Induction in the Synthesis of Dinucleoside Phosphorothioates from 2-Oxo-1,3,2-dithiaphospholane Nucleoside Derivatives

  摘要：

  The nucleoside derivatives, containing at 3'-O or 5'-O-position 2-oxo-1,3,2-dithiaphospholane function were found to react in the presence of DBU with a hydroxyl group of appropriately protected nucleosides to yield, after deprotection, dinucleoside phosphorothioates in moderate yields. An asymmetric induction connected with the formation of new chiral phosphorothioate center has been examined.

  DOI：

  10.1080/10426500902947898