Acetic acid (Z)-3,7-dimethyl-10-(naphthalen-1-ylamino)-dec-6-enyl ester | 263012-48-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Acetic acid (Z)-3,7-dimethyl-10-(naphthalen-1-ylamino)-dec-6-enyl ester
• CAS: 263012-48-2
• 化学式: C₂₄H₃₃NO₂
• 分子量: 367.532
• InChiKey: RVLTUNOYBCBFPL-OCKHKDLRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.35
• 重原子数：
  27.0
• 可旋转键数：
  11.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  38.33
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  Acetic acid (Z)-3,7-dimethyl-10-(naphthalen-1-ylamino)-dec-6-enyl ester 在 potassium carbonate 作用下， 以 甲醇 为溶剂， 生成 (Z)-3,7-Dimethyl-10-(naphthalen-1-ylamino)-dec-6-en-1-ol
  参考文献：
  名称：

  Synthesis of dolichyl phosphate derivatives with fluorescent label at the ω-end of the chain, new tools to study protein glycosylation

  摘要：

  Derivatives of dolichyl phosphate (Dol-P) with 2-aminopyridine or 1-aminonaphtalene fluorophore groups at the omega-end of the chain were synthesized. These products serve as substrates for recombinant yeast Dol-P-mannose synthase. Fluorescence resonance energy transfer between a Trp residue of the enzyme and the 1-aminonaphtalene group of the Dol-P analogue was demonstrated. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00662-9
• 作为产物：
  描述：

  3,7,11-trimethyl-10,11-epoxydodec-6Z-en-2-yl acetate 在 3 A molecular sieve 、 高碘酸 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 反应 5.5h， 生成 Acetic acid (Z)-3,7-dimethyl-10-(naphthalen-1-ylamino)-dec-6-enyl ester
  参考文献：
  名称：

  Synthesis of dolichyl phosphate derivatives with fluorescent label at the ω-end of the chain, new tools to study protein glycosylation

  摘要：

  Derivatives of dolichyl phosphate (Dol-P) with 2-aminopyridine or 1-aminonaphtalene fluorophore groups at the omega-end of the chain were synthesized. These products serve as substrates for recombinant yeast Dol-P-mannose synthase. Fluorescence resonance energy transfer between a Trp residue of the enzyme and the 1-aminonaphtalene group of the Dol-P analogue was demonstrated. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00662-9