chloropalladium(1+);1-(2H-naphthalen-2-id-1-yl)ethanamine | 190125-95-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: chloropalladium(1+);1-(2H-naphthalen-2-id-1-yl)ethanamine
• CAS: 190125-95-2
• 化学式: C₂₄H₂₄Cl₂N₂Pd₂
• 分子量: 624.214
• InChiKey: ILMBKADFQWONJH-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  6.69
• 重原子数：
  30
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  chloropalladium(1+);1-(2H-naphthalen-2-id-1-yl)ethanamine 、 dichlorobis[(+/-)-benzylcyclohexylphenylphosphine]nickel(II) 以 四氢呋喃 为溶剂， 生成 (C10H6CH(CH3)(NH2))PdCl(benzylcyclohexylphenylphosphine)
  参考文献：
  名称：

  Resolution of Benzylcyclohexylphenylphosphine by Palladium(II)−Amine Metallacycles. A New Ligand for Asymmetric Hydrovinylation

  摘要：

  The synthesis of benzylcyclohexylphenylphosphine and its resolution by means of optically active palladium metallacycles are reported. The absolute configuration of (R-C,S-P)-[PdCl(C6H4CHMeNMe2)(PBzCyPh)] has been determined by single-crystal X-ray analyses. The allyl complex [Pd(eta(3)-2-MeC3H4)(PBzCyPh)S]BF4, prepared in situ from [Pd(eta(3)-2-MeC3H4)Cl(PBzCyPh)] and AgBF4 in CH2Cl2 solution, was used as a precatalyst for asymmetric hydrovinylatiom of styrene and 2-vinylnaphthalene. This system permits the synthesis of 3-phenyl-1-butene and 3-(2-naphthyl)-1-butene with good ee values working in very mild conditions of temperature (15 degrees C).

  DOI：

  10.1021/om990302d