2-(1-bromopropan-2-yloxy)naphthalene | 876380-72-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(1-bromopropan-2-yloxy)naphthalene
• 英文别名: 2-(1-Bromopropan-2-yloxy)naphthalene
• CAS: 876380-72-2
• 化学式: C₁₃H₁₃BrO
• 分子量: 265.15
• InChiKey: ZYIWGVWSSRTHQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-(1-bromopropan-2-yloxy)naphthalene 在 potassium carbonate 作用下， 以 四氢呋喃 为溶剂， 反应 26.0h， 生成 1,3-bis[2-(naphthalen-2-yloxy)propyl]imidazolium bromide
  参考文献：
  名称：

  A highly active ionic liquid catalyst for Morita–Baylis–Hillman reaction

  摘要：

  The Morita-Baylis-Hillman reaction is an efficient carbon-carbon bond forming reaction for the preparation of alpha-methylene-beta-hydroxycarbonyl compounds. A new and highly active di-naphthalene imidazolium salt has been synthesized. We have found that 1, 3-bis[2-(naphthalene-2-yloxy)propyl]imidazolium bromid promoted the Morita-Baylis-Hillman reaction of various aryl aldehyde compounds in the absence of solvents. Our studies show that the Morita-Baylis-Hillman reaction by the influence of ionic liquid to give a high yield and short reaction time. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2005.10.048
• 作为产物：
  描述：

  methyl 2-(naphthalen-2-yloxy)propanoate 在 吡啶 、 sodium tetrahydroborate 、 lithium carbonate 、 lithium bromide 作用下， 以 四氢呋喃 、 二氯甲烷 、 丙酮 为溶剂， 反应 45.5h， 生成 2-(1-bromopropan-2-yloxy)naphthalene
  参考文献：
  名称：

  A highly active ionic liquid catalyst for Morita–Baylis–Hillman reaction

  摘要：

  The Morita-Baylis-Hillman reaction is an efficient carbon-carbon bond forming reaction for the preparation of alpha-methylene-beta-hydroxycarbonyl compounds. A new and highly active di-naphthalene imidazolium salt has been synthesized. We have found that 1, 3-bis[2-(naphthalene-2-yloxy)propyl]imidazolium bromid promoted the Morita-Baylis-Hillman reaction of various aryl aldehyde compounds in the absence of solvents. Our studies show that the Morita-Baylis-Hillman reaction by the influence of ionic liquid to give a high yield and short reaction time. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2005.10.048

文献信息

• A highly active ionic liquid catalyst for Morita–Baylis–Hillman reaction
  作者：Yu-Sheng Lin、Chiao-Yang Lin、Chih-Wei Liu、Thomas Y.R. Tsai

  DOI：10.1016/j.tet.2005.10.048

  日期：2006.1

  The Morita-Baylis-Hillman reaction is an efficient carbon-carbon bond forming reaction for the preparation of alpha-methylene-beta-hydroxycarbonyl compounds. A new and highly active di-naphthalene imidazolium salt has been synthesized. We have found that 1, 3-bis[2-(naphthalene-2-yloxy)propyl]imidazolium bromid promoted the Morita-Baylis-Hillman reaction of various aryl aldehyde compounds in the absence of solvents. Our studies show that the Morita-Baylis-Hillman reaction by the influence of ionic liquid to give a high yield and short reaction time. (c) 2005 Elsevier Ltd. All rights reserved.