1-O-pentadecyl-sn-glycero-3-phosphocholine | 111858-51-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: 1-O-pentadecyl-sn-glycero-3-phosphocholine
• 英文别名: 1-Pentadecyl-sn-glycero-3-phosphocholine；[(2R)-2-hydroxy-3-pentadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
• CAS: 111858-51-6
• 化学式: C₂₃H₅₀NO₆P
• 分子量: 467.627
• InChiKey: PPXKEQMZYFQYCJ-HSZRJFAPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  31
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  88
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  丁酸酐 、 1-O-pentadecyl-sn-glycero-3-phosphocholine 在 吡啶 作用下， 反应 2.0h， 生成
  参考文献：
  名称：

  Fruiting-lnducing Activity and Antifungal Properties of Lipid Components in Members of Annelida.

  摘要：

  Fruiting-inducing activity and antifungal properties of lipid components in the phylum Annelida were examined. Some amphoteric cerebrosides carrying a phosphocholine group showed fruiting-inducing activity on Schizophyllum commune, and one of them possessed activity comparable to that of Sch II, the most potent substance known. Furthermore, alkyl lysophosphatidylcholines were found to have an inhibitory effect on the growth of phytopathogenic fungi, Alternaria kikuchiana and Phomopsis mali. The relationship between structure and biological activities is discussed.

  DOI：

  10.1248/cpb.45.1702