3-acetoxy-4-methylergost-7-ene

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3-acetoxy-4-methylergost-7-ene
• 英文别名: [17-(5,6-dimethylheptan-2-yl)-4,10,13-trimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
• 化学式: C₃₁H₅₂O₂
• 分子量: 456.753
• InChiKey: MPSMORKTRDBZSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-methylergost-7-en-3-ol 、 乙酸酐 在 吡啶 作用下， 反应 0.5h， 生成 3-acetoxy-4-methylergost-7-ene
  参考文献：
  名称：

  EP1731527

  摘要：

  公开号：

文献信息

• DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS
  申请人：MORINAGA MILK INDUSTRY CO., LTD.

  公开号：EP1882477A1

  公开（公告）日：2008-01-30

  3-O-β-D-Glucopyranosyl-4-methyl-ergost-7-en-3-ol or a composition containing 0.001 to 10% by dry mass of the aforementioned compound, which is an extract of a plant of the family Liliaceae or a fraction thereof containing the compound, is used as an active ingredient of a drug for improving pancreatic functions.

  3-O-β-D-吡喃葡萄糖基-4-甲基麦角甾-7-烯-3-醇或含有 0.001%至 10%（以干质量计）上述化合物的组合物，是百合科植物的提取物或含有该化合物的馏分，可用作改善胰腺功能药物的活性成分。
• VISCERAL FAT ACCUMULATION INHIBITOR
  申请人：MORINAGA MILK INDUSTRY CO., LTD.

  公开号：EP1927361A1

  公开（公告）日：2008-06-04

  To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity considered to be a main factor of metabolic syndrome, there is provided an agent or a food or drink, including as an active ingredient 3-O-β-D-glucopyranosyl-4-methylergost-7-en-3-ol, an organic solvent extract, a hot water extract, a squeezed liquid of a Liliaceae plant or a fraction thereof which contains the compound.

  为了减少腹腔中积聚的脂肪量，预防或改善被认为是代谢综合征主要因素的内脏脂肪型肥胖，提供了一种制剂或食品或饮料，包括作为活性成分的 3-O-β-D-吡喃葡萄糖基-4-甲基麦角甾-7-烯-3-醇、有机溶剂提取物、热水提取物、百合科植物的挤压液或其馏分，其中含有该化合物。
• GLYCOSIDE HAVING 4-METHYLERGOST-7-EN-3-OL SKELETON AND DRUG FOR AMELIORATING HYPERGLYCEMIA
  申请人：MORINAGA MILK INDUSTRY CO., LTD.

  公开号：EP1731527B1

  公开（公告）日：2012-10-10
• Glycoside Having 4-Methylergost-7-En-3-Ol Skeleton and Hyperglycemia Improving Agent
  申请人：Higuchi Ryuuichi

  公开号：US20080044500A1

  公开（公告）日：2008-02-21

  3-O-β-D-Glucopyranosyl-4-methylergost-7-en-3-ol or a composition containing 0.001% by mass or more of the aforementioned compound, which is an extract of a plant of the family Liliaceae containing the compound or a fraction thereof, is used as an active ingredient of a hyperglycemia improving agent.
• Drug And Food Or Drink For Improving Pancreatic Functions
  申请人：Tanaka Miyuki

  公开号：US20080125379A1

  公开（公告）日：2008-05-29

  3-O-β-D-Glucopyranosyl-4-methyl-ergost-7-en-3-ol or a composition containing 0.001 to 10% by dry mass of the aforementioned compound, which is an extract of a plant of the family Liliaceae or a fraction thereof containing the compound, is used as an active ingredient of a drug for improving pancreatic functions.