sec-Butyl-but-(E)-ylidene-amine | 26891-14-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: sec-Butyl-but-(E)-ylidene-amine
• 英文别名: N-butan-2-ylbutan-1-imine
• CAS: 26891-14-5
• 化学式: C₈H₁₇N
• 分子量: 127.23
• InChiKey: QIFPHNOQNKONCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  sec-Butyl-but-(E)-ylidene-amine 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 24.0h， 生成 二仲丁胺
  参考文献：
  名称：

  A Convergent One-Pot Synthesis of Secondary Amines via Aza-Wittig Reaction

  摘要：

  Secondary amines are obtained in moderate-good yields by reduction of crude imines prepared from N-alkyltriethoxyiminophosphoranes and aldehydes via the aza-Wittig reaction. N-Alkyltriethoxyiminophosphoranes are synthesized by one-pot azidation of alkyl bromides followed by Staudinger reaction.

  DOI：

  10.1080/00397919208021323
• 作为产物：
  描述：

  sec-Butyl-phosphorimidic acid triethyl ester 、 正丁醛 以 苯 为溶剂， 反应 3.0h， 生成 sec-Butyl-but-(E)-ylidene-amine
  参考文献：
  名称：

  A Convergent One-Pot Synthesis of Secondary Amines via Aza-Wittig Reaction

  摘要：

  Secondary amines are obtained in moderate-good yields by reduction of crude imines prepared from N-alkyltriethoxyiminophosphoranes and aldehydes via the aza-Wittig reaction. N-Alkyltriethoxyiminophosphoranes are synthesized by one-pot azidation of alkyl bromides followed by Staudinger reaction.

  DOI：

  10.1080/00397919208021323

文献信息

• A Convergent One-Pot Synthesis of Secondary Amines via Aza-Wittig Reaction
  作者：Gajda、Koziara、Osowska-Pacewicka、Zawadzki、Zwierzak

  DOI：10.1080/00397919208021323

  日期：1992.7

  Secondary amines are obtained in moderate-good yields by reduction of crude imines prepared from N-alkyltriethoxyiminophosphoranes and aldehydes via the aza-Wittig reaction. N-Alkyltriethoxyiminophosphoranes are synthesized by one-pot azidation of alkyl bromides followed by Staudinger reaction.