1-(3'-methoxy-4'-hydroxyphenyl)-1-hydroxy-2-methylpropane | 58105-63-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 1-(3'-methoxy-4'-hydroxyphenyl)-1-hydroxy-2-methylpropane
• 英文别名: 1-(4-hydroxy-3-methoxyphenyl)-2-methylpropanol；1-(4-hydroxy-3-methoxy-phenyl)-2-methyl-propan-1-ol；1-(4-Hydroxy-3-methoxy-phenyl)-2-methylpropanol；4-(1-hydroxy-2-methylpropyl)-2-methoxyphenol
• CAS: 58105-63-8
• 化学式: C₁₁H₁₆O₃
• 分子量: 196.246
• InChiKey: DBEHHIQWXXOBRI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(3'-methoxy-4'-hydroxyphenyl)-1-hydroxy-2-methylpropane 在 硫酸 、 水 作用下， 反应 3.0h， 生成 7-hydroxy-6-methoxy-1,3,3-trimethyl-3,4-dihydroisoquinoline
  参考文献：
  名称：

  3,3-二甲基-3,4-二氢异喹啉的7-（或6-）羟基衍生物的合成

  摘要：

  当用氰基乙酸酯浓溶液处理时。H 2 SO 4 1-（4-羟基-3-甲氧基苯基）-和1-（3-羟基-4-甲氧基苯基）-2-甲基丙烷-1-醇形成乙基7-羟基-6-甲氧基-3,3-二甲基（或6-羟基-7-甲氧基-3,3-二甲基）-1,2,3,4-四氢异喹啉-1-乙酸酯。

  DOI：

  10.1007/s10593-009-0268-9
• 作为产物：
  描述：

  异丙基溴化镁 、 香草醛 生成 1-(3'-methoxy-4'-hydroxyphenyl)-1-hydroxy-2-methylpropane
  参考文献：
  名称：

  Roberti et al., Journal of the American Chemical Society, 1950, vol. 72, p. 5760,5761

  摘要：

  DOI：

文献信息

• COMPOUNDS AND METHODS OF TREATING OBESITY
  申请人：YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

  公开号：US20140309273A1

  公开（公告）日：2014-10-16

  Provided are new fatty acid derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, e.g., as agents for the treatment of obesity and related disorders, and for improving cognition.

  提供了新的脂肪酸衍生物，其制备方法，包括这些化合物的制药组合物，以及使用这些化合物和组合物的方法，例如作为治疗肥胖症和相关疾病的药物，以及改善认知功能的药物。
• Rottendorf,H. et al., Australian Journal of Chemistry, 1965, vol. 18, p. 1759 - 1773
  作者：Rottendorf,H. et al.

  DOI：——

  日期：——
• NITRIFICATION INHIBITORS
  申请人：BASF SE

  公开号：US20170036969A1

  公开（公告）日：2017-02-09

  The present invention relates to novel nitrification inhibitors of formula I. Moreover, the invention relates to the use of these novel nitrification inhibitors for reducing nitrification, as well as agrochemical mixtures and compositions comprising the nitrification inhibitors. Further encompassed by the present invention are methods for reducing nitrification comprising the treatment of plants, soil and/or loci with said nitrification inhibitors, and methods for treating a fertilizer or a composition by applying said nitrification inhibitor.
• Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides
  申请人：BASF SE

  公开号：US20170181435A1

  公开（公告）日：2017-06-29

  A composition including (a) at least one (thio)phosphoric acid triamide (T) according to the general formula (Ia) R a1 R a2 N—P(X)(NH 2 ) 2 (Ia) wherein X is oxygen or sulfur; R a1 is a C 1 to C 20 alkyl, C 3 to C 20 cycloalkyl, C 6 to C 20 aryl, or dialkylaminocarbonyl group; R a2 is H, or R a1 and R a2 together with the nitrogen atom linking them define a 5- or 6-membered saturated or unsaturated heterocyclic radical, which optionally comprises 1 or 2 further heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur; and (b) at least one biopesticide.
• Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides
  申请人：BASF SE

  公开号：US20170223964A1

  公开（公告）日：2017-08-10

  A composition including (a) at least one (thio)phosphoric acid triamide (T) according to the general formula (Ia) R a1 R a2 N—P(X)(NH 2 ) 2 (Ia) wherein X is oxygen or sulfur; R a1 is a C 1 to C 20 alkyl, C 3 to C 20 cycloalkyl, C 6 to C 20 aryl, or dialkylaminocarbonyl group; R a2 is H; or R a1 and R a2 together with the nitrogen atom linking them define a 5- or 6-membered saturated or unsaturated heterocyclic radical, which optionally comprises 1 or 2 further heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur; and (b) at least one specific herbicide.