cladosporol

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: cladosporol
• 英文别名: (1aR,2R,7aR)-2,3-dihydroxy-6-[(1R)-5-hydroxy-4-oxo-2,3-dihydro-1H-naphthalen-1-yl]-2,7a-dihydro-1aH-naphtho[2,3-b]oxiren-7-one
• 化学式: C₂₀H₁₆O₆
• 分子量: 352.343
• InChiKey: LARAKOUQDSHWJV-RORDDOKRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  26
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  107
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  cladosporol 以 二氯甲烷 为溶剂， 生成 cladosporol B
  参考文献：
  名称：

  Secondary mould metabolites of Cladosporium tenuissimum, a hyperparasite of rust fungi

  摘要：

  Investigation of the extracts of a culture of Cladosporium tenuissimum, a known hyperparasite of several rust fungi, gave rise to the isolation of cladosporols B-E (2-5). Their structure and stereochemistry were elucidated on the basis of H-1 and C-13 NMR evidence and CD measures.Cladosporols 1-5 were active in inhibiting the urediniospore germination of the bean rust agent Uromyces appendiculatus. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2004.03.013

文献信息

• Secondary mould metabolites of Cladosporium tenuissimum, a hyperparasite of rust fungi
  作者：Gianluca Nasini、Alberto Arnone、Gemma Assante、Adriana Bava、Salvatore Moricca、Alessandro Ragazzi

  DOI：10.1016/j.phytochem.2004.03.013

  日期：2004.7

  Investigation of the extracts of a culture of Cladosporium tenuissimum, a known hyperparasite of several rust fungi, gave rise to the isolation of cladosporols B-E (2-5). Their structure and stereochemistry were elucidated on the basis of H-1 and C-13 NMR evidence and CD measures.Cladosporols 1-5 were active in inhibiting the urediniospore germination of the bean rust agent Uromyces appendiculatus. (C) 2004 Elsevier Ltd. All rights reserved.