romucosine H | 344928-15-0

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 阿朴菲
• 英文名称: romucosine H
• 英文别名: N-(methoxycarbonyl)norisocorydine；Methyl (6aR)-4,5,6a,7-tetrahydro-11-hydroxy-1,2,10-trimethoxy-6H-dibenzo[de,g]quinoline-6-carboxylate；methyl (6aR)-11-hydroxy-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-carboxylate
• CAS: 344928-15-0
• 化学式: C₂₁H₂₃NO₆
• 分子量: 385.417
• InChiKey: JWSAYTXQWHOMHU-CYBMUJFWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  77.5
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  氯甲酸甲酯 、 (-)-norisocorydine 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.17h， 以5 mg的产率得到romucosine H
  参考文献：
  名称：

  Four alkaloids from Annona cherimola

  摘要：

  Four alkaloids, annocherine A, annocherine B, cherianoine, and romucosine H, along with one known alkaloid, artabonatine B, were isolated from the MeOH extract of the stems of Annona cherimola. Their structures were identified on the basis of both analysis of their spectral data and from chemical evidence. (C) 2001 Elsevier Science Ltd. Air rights reserved.

  DOI：

  10.1016/s0031-9422(00)00486-6

文献信息

• Four alkaloids from Annona cherimola
  作者：Chung-Yi Chen、Fang-Rong Chang、Wen-Bin Pan、Yang-Chang Wu

  DOI：10.1016/s0031-9422(00)00486-6

  日期：2001.4

  Four alkaloids, annocherine A, annocherine B, cherianoine, and romucosine H, along with one known alkaloid, artabonatine B, were isolated from the MeOH extract of the stems of Annona cherimola. Their structures were identified on the basis of both analysis of their spectral data and from chemical evidence. (C) 2001 Elsevier Science Ltd. Air rights reserved.