(benzothiazol-2-yl) tert-butyl sulfone | 21554-43-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: (benzothiazol-2-yl) tert-butyl sulfone
• 英文别名: 2-(2-methyl-propane-2-sulfonyl)-benzothiazole；2-tert-butylsulfonyl-1,3-benzothiazole
• CAS: 21554-43-8
• 化学式: C₁₁H₁₃NO₂S₂
• 分子量: 255.362
• InChiKey: BMMQDUGWDZXDFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  83.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (benzothiazol-2-yl) tert-butyl sulfone 在 正丁基锂 作用下， 以 四氢呋喃 、 乙醚 、 正己烷 为溶剂， 反应 3.42h， 生成 1,2-bis[2-(benzothiazol-2-yl)benzothiophen-3-yl]hexafluorocyclopentene
  参考文献：
  名称：

  摘要：

  Dithienylethenes containing the thiophene rings with benzothiazolyl substituents in position 2 were synthesized. 1,2-Bis]2-(benzothiazol-2-yl)benzothiophen-3-yl]hexafluorocyclopentene and 1,2-bis]2,5-di(benzothiazol-2-yl)-3-thienyl]hexafluorocyclopentene possess photochromic properties. The open forms of 1,2-bis(2-benzothiazolyhetaryl)ethenes fluoresce, but introduction of the benzothiazole rings into dihetarylethenes significantly lowers the fatigue resistance of photochromes and favors thermal reversibility.

  DOI：

  10.1023/a:1015052017059

文献信息

• Highly emissive B←N unit containing four-coordinate C,N-Chelated organoboron compound for the detection of fluoride ions
  作者：Ni Yan、Fengyan Wang、Junji Wei、Jiale Song、Luke Yan、Jishun Luo、Zhongyuan Fang、Zhijun Wang、Weidong Zhang、Gang He

  DOI：10.1016/j.dyepig.2019.03.057

  日期：2019.7

  The highly emissive B←N unit containing four-coordinate C,N-chelated organoboron compound, 2 was synthesized. This air and moisture stable compound can be used as a turn-off type fluorescent fluoride (F−) sensor in THF with good selectivity and reversibility. The DFT calculation and the fluorescence quenching titration results showed that the mechanism of the sensing process was based on a competing

  合成了含有四配位C，N-螯合的有机硼化合物2的高发射B←N单元。此空气和湿气稳定的化合物可被用作一个关断型荧光氟化物（F - ）传感器在THF与良好的选择性和可逆性。DFT计算和荧光猝灭滴定结果表明，传感过程的机理是基于竞争反应：以开放形式形成具有较强B F键的2-F取代了具有B←N键的2-在一个封闭的形式当Fc -被引入，导致显著吸收变化和荧光淬灭。
• Hemiasterlin Derivatives and Uses Thereof
  申请人：Campagna Silvio A.

  公开号：US20080108820A1

  公开（公告）日：2008-05-08

  The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R 1 -R 7 , X 1 , X 2 , R, Q, and n are as defined herein.
• US8188216B2
  申请人：——

  公开号：US8188216B2

  公开（公告）日：2012-05-29
• ——
  作者：M. M. Krayushkin、F. M. Stoyanovich、O. Yu. Zolotarskaya、I. V. Murav"ev、A. Yu. Martynkin、B. M. Uzhinov

  DOI：10.1023/a:1015052017059

  日期：——

  Dithienylethenes containing the thiophene rings with benzothiazolyl substituents in position 2 were synthesized. 1,2-Bis]2-(benzothiazol-2-yl)benzothiophen-3-yl]hexafluorocyclopentene and 1,2-bis]2,5-di(benzothiazol-2-yl)-3-thienyl]hexafluorocyclopentene possess photochromic properties. The open forms of 1,2-bis(2-benzothiazolyhetaryl)ethenes fluoresce, but introduction of the benzothiazole rings into dihetarylethenes significantly lowers the fatigue resistance of photochromes and favors thermal reversibility.