4-氯-2-己基苯酚 | 18979-94-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 4-氯-2-己基苯酚
• 英文名称: n-Hexyl-p-Chlorophenol
• 英文别名: 4-chloro-2-hexyl-phenol；5-Chlor-2-hydroxy-1-hexyl-benzol；4-Chlor-2-hexyl-phenol；Phenol, 4-chloro-2-hexyl-；4-chloro-2-hexylphenol
• CAS: 18979-94-7
• 化学式: C₁₂H₁₇ClO
• 分子量: 212.719
• InChiKey: UUBASQRIVIRMIQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-氯-2-己基苯酚 在 三氯化铝 作用下， 生成 1-(5-chloro-3-hexyl-2-hydroxy-phenyl)-heptan-1-one
  参考文献：
  名称：

  Vogelsang; Wagner-Jauregg, Justus Liebigs Annalen der Chemie, 1950, vol. 568, p. 116,125

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 amalgamated zinc 作用下， 生成 4-氯-2-己基苯酚
  参考文献：
  名称：

  The Alkyl Derivatives of Halogen Phenols and their Bactericidal Action. I. Chlorophenols

  摘要：

  DOI：

  10.1021/ja01333a058

文献信息

• MEDICAL ADHESIVE COMPOSITIONS
  申请人：Liu Hongbo

  公开号：US20110230561A1

  公开（公告）日：2011-09-22

  A medical adhesive composition comprising, based upon the total weight of the composition, from about 50 wt. % to about 99.9 wt. % of one or more α-cyanoacrylate monomers and from about 0.1 wt. % to about 5 wt. % of one or more non-steroidal anti-inflammatory drugs (NSAIDs). Suitable NSAIDs include ibuprofen and acetaminophen. The resulting compositions provide enhances fibroblast proliferation and reduced cytotoxicity compared to compositions that do not contain NSAID.

  一种医用粘合剂组合物，包括以组合物的总重量为基础，约50重量％至约99.9重量％的一种或多种α-氰基丙烯酸酯单体和约0.1重量％至约5重量％的一种或多种非甾体抗炎药（NSAIDs）。适用的NSAIDs包括布洛芬和对乙酰氨基酚。与不含NSAID的组合物相比，所得到的组合物提供了增强成纤维细胞增殖和减少细胞毒性的效果。
• ACTIVE DELIVERY SYSTEMS FORMULATIONS
  申请人：HOMOLA Andrew M.

  公开号：US20100040565A1

  公开（公告）日：2010-02-18

  The present invention relates to active delivery system formulations, and methods of making and using the same. Said formulations, when applied to a substrate surface, form a protective coating on the surface and permit constituent active agents to act on the surface and in the surrounding medium.

  本发明涉及活性传递系统配方，以及制备和使用这些配方的方法。当这些配方应用到基底表面时，在表面形成一层保护性涂层，并允许组分活性剂在表面和周围介质中起作用。
• A hydrolyzable resin composition and an antifouling coating composition containing the same
  申请人：Nippon Paint Co., Ltd.

  公开号：EP0204456A1

  公开（公告）日：1986-12-10

  A hydrolyzable resin composition based on a resin having at least one side chain bearing a particular metal containing terminal group. There is also provided an antifouling coating composition containing such a hydrolyzable resin composition as a resinous vehicle. More particularly, the resin has at least one side chain bearing at least one terminal group of the formula where M is a metal selected from zinc, copper and tellurium, and X and R are particularly defined.

  一种可水解树脂组合物，它基于一种树脂，该树脂至少有一个侧链带有特定的含金属末端基团。此外，还提供了一种防污涂料组合物，其中含有这种作为树脂载体的可水解树脂组合物。更具体地说，该树脂具有至少一条侧链，其中至少含有一个式中的末端基团 其中 M 是选自锌、铜和碲的金属，X 和 R 特别定义。
• Resinous composition capable of releasing a bioactive substance at a controlled rate
  申请人：Nippon Paint Co., Ltd.

  公开号：EP0220965A2

  公开（公告）日：1987-05-06

  A bioactive substance control-releasing resinous composition comprising a resin having main chain and side chains, at least one side chain bearing at the end portion thereof an organic acid moiety having a biological activity through a metal ester bonding. The resin is hydrolyzed in an ionic atmosphere at a controlled rate to generate a bioactive substance as well as metal ions and is useful in various field and especially as resinous vehicle of coating composition.

  一种生物活性物质控制释放树脂组合物，由具有主链和侧链的树脂组成，其中至少一条侧链的末端部分通过金属酯键连接具有生物活性的有机酸分子。该树脂在离子气氛中以可控速率水解，生成生物活性物质和金属离子，可用于各种领域，特别是用作涂料组合物的树脂载体。
• Disintegration type resin particles, its preparation and coating composition containing the same
  申请人：Nippon Paint Co., Ltd.

  公开号：EP0286243A1

  公开（公告）日：1988-10-12

  Disintegration type resin particles having an average grain diameter of 0.01 to 250u. and being composed of a crosslinked resin having at least one crosslinking structure carried metal ester bond of the formula: R1 is a monovalent, bioactive organic acid residue; M stands for a polyvalent metal having a valence of 3 or more; m is an integer of 2 or more; n is an integer of 1 or more, providing that the sum of m and n is equal to the valence of said metal @, and a coating composition containing said resin particles are provided. The coating obtained is characterized in that it is gradually hydrolyzed in an ionic atmosphere as in sea water and dissolved out, liberating a bioactive organic acid as well as metal ions.

  崩解型树脂颗粒，其平均粒径为 0.01 至 250u： R1 是一价的生物活性有机酸残基；M 代表价数为 3 或更多的多价金属；m 是 2 或更多的整数；n 是 1 或更多的整数，条件是 m 和 n 的总和等于所述金属 @ 的价数；本发明还提供了一种含有所述树脂颗粒的涂料组合物。所获得的涂层的特征在于，它在海水等离子环境中逐渐水解并溶解，释放出生物活性有机酸和金属离子。