Azane;sulfurous acid

• 分子结构分类: 无机化合物 - 均质非金属化合物 - 非金属氧阴离子化合物
• 英文名称: Azane;sulfurous acid
• 化学式: H8N2O3S
• 分子量: 116.14
• InChiKey: PQUCIEFHOVEZAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.25
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  84.4
• 氢给体数：
  2
• 氢受体数：
  4

ADMET

毒理性

• 解毒与急救

基本治疗：建立专利气道。如有必要，进行吸痰。观察呼吸不足的迹象，如有必要，协助通气。通过非重复呼吸面罩以10至15升/分钟的速度给予氧气。监测肺水肿的迹象，并在必要时进行治疗……。监测休克的迹象，并在必要时进行治疗……。对于眼睛污染，立即用水冲洗眼睛。在运输过程中，用生理盐水连续冲洗每只眼睛……。不要使用催吐剂。对于摄入，如果患者能够吞咽，有强烈的干呕反射，并且不流口水，用水冲洗口腔，并给予5毫克/千克，最多200毫升的水进行稀释……。不要尝试中和。/氨和相关化合物/

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for signs of pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mg/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize. /Ammonia and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

高级治疗：如果出现上呼吸道阻塞的迹象，或者患者无意识或有严重肺水肿，考虑进行口咽或鼻咽气管插管以控制气道。使用气囊阀面罩装置的正压通气技术可能有益。监测心率和必要时治疗心律失常... 开始静脉输液，使用D5W/SRP：“保持开放”，最低流速... 如果出现低血容量的迹象，使用乳酸钠林格氏液。注意液体过载的迹象。考虑使用药物治疗肺水肿... 对于伴有低血容量迹象的低血压，谨慎给予液体。如果患者血容量正常但血压低，考虑使用血管加压药。注意液体过载的迹象... 使用丙美卡因氢氯化物协助眼部冲洗... /氨及其相关化合物/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control if signs of upper airway obstruction are present or if the patient is unconscious or has severe pulmonary edema. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ammonium and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

基本治疗：建立专利气道。如有必要，进行吸痰。观察呼吸不足的迹象，如有必要，协助通气。通过非循环呼吸面罩以10至15升/分钟的速度给予氧气。监测肺水肿，并在必要时进行治疗……。预期癫痫发作，并在必要时进行治疗……。对于眼睛污染，立即用水冲洗眼睛。在运输过程中，用生理盐水连续冲洗每只眼睛……。不要使用催吐剂。对于误食，如果患者能吞咽、有强烈的呕吐反射且不流口水，则用水冲洗口腔，并给予5毫升/千克，最多200毫升的水进行稀释……。给予活性炭……。在去污后，用干无菌敷料覆盖皮肤烧伤……。/硫和相关化合物/

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 m1/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Sulfur and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

高级治疗：对于无意识的病人，考虑进行口咽或鼻咽气管插管以控制气道。在上呼吸道阻塞的第一个迹象出现时，可能需要早期插管。监测心率和必要时治疗心律失常... 开始静脉输液，使用5%葡萄糖盐水/生理盐水：为了保持开放，最低流速... 如果出现低血容量的迹象，使用乳酸钠林格液。注意液体过载的迹象。考虑使用药物治疗肺水肿... 使用地西泮（安定）治疗癫痫... 对于伴有低血容量迹象的低血压，谨慎给予液体。如果液体量正常而出现低血压，考虑使用血管加压药。注意液体过载的迹象... 使用丙美卡因盐酸协助眼部冲洗... /硫磺及相关化合物/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Early intubation at the first sign of upper airway obstruction may be necessary. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . Treat seizures with diazepam (Valium) ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Sulfur and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 人类毒性摘录

如果吞下，它们可能会通过释放硫酸而刺激胃部。/亚硫酸盐/

... If swallowed they may cause irritation of the stomach by liberating sulfurous acid. /Sulfites/

来源:Hazardous Substances Data Bank (HSDB)

反应信息

• 作为反应物：
  描述：

  Azane;sulfurous acid 生成 硫化氢
  参考文献：
  名称：

  RAYMOND, BERTRAND;MILANDE, NICOLAS;ZUFFI, ODILE

  摘要：

  DOI：
• 作为产物：
  描述：

  二氧化硫 、 ammonium hydroxide 生成 Azane;sulfurous acid
  参考文献：
  名称：

  KIM, P. P.;KOZLOV, R. V.;NIKANDROV, I. S., ZH. PRIKL. XIMII, 62,(1989) N, S. 843-845

  摘要：

  DOI：

文献信息

• Process for regenerating brines containing sodium sulfites and sulfates
  申请人：Institut Francais du Petrole

  公开号：US04164543A1

  公开（公告）日：1979-08-14

  Process for regenerating brines containing simultaneously sodium sulfites and sulfates so as to produce sulfur dioxide and an alkaline solution usable for absorbing sulfur dioxide, comprising contacting the brine with ammonium bisulfate, sodium bisulfate and ammonium sulfite to produce sulfur dioxide and an enriched solution of sodium sulfate and ammonium sulfate, which is reacted with CO.sub.2 and ammonia to obtain solid sodium bicarbonate which is decomposed to form CO.sub.2 and an enriched solution of ammonium sulfate, containing dissolved ammonium bicarbonate, which is heated with a reducing agent so as to decompose the ammonium sulfate to ammonia and ammonium bisulfate which is partly reduced to gaseous ammonia and sulfur dioxide, said process including several recycling steps.

  用于再生同时含有亚硫酸钠和硫酸盐的卤水，以产生二氧化硫和可用于吸收二氧化硫的碱性溶液的过程，包括将卤水与硫酸氢铵、硫酸氢钠和亚硫酸铵接触，以产生二氧化硫和富集的硫酸钠和硫酸铵溶液，该溶液与CO.sub.2和氨反应以获得固态碳酸氢钠，分解后形成CO.sub.2和富集的硫酸铵溶液，其中含有溶解的碳酸氢铵，该溶液与还原剂加热以分解成氨和硫酸氢铵，后者部分还原为氨气和二氧化硫，该过程包括几个循环步骤。
• Process for the continuous manufacture of crystallized ammonium
  申请人：Hoechst Aktiengesellschaft

  公开号：US03937793A1

  公开（公告）日：1976-02-10

  Crystallized ammonium thiosulfate is manufactured by converting ammonia with oxygen containing sulfur dioxide in ammonium thiosulfate solution to ammonium bisulfite and ammonium sulfite in a first step, while maintaining a pH of from 5.5 to 7.0 and a reaction temperature of up to 80.degree.C. In a second step, the ammonium bisulfite and ammonium sulfite in the solution are converted with ammonia and sulfur to ammonium thiosulfate.

  结晶硫代硫酸铵的制造过程是通过将含氧二氧化硫的氨水嘧磺酸溶液转化为硫代硫酸铵和亚硫酸铵，保持pH值在5.5至7.0之间，反应温度高达80度。在第二步中，溶液中的硫代硫酸铵和亚硫酸铵通过与氨和硫反应转化为硫代硫酸铵。
• Permanent flame retardant and anti-smoldering compositions
  申请人：——

  公开号：US04514326A1

  公开（公告）日：1985-04-30

  When alkali metal and/or alkaline earth metal tetraborates in a water suspension are suitably treated with ammonia and sulfuric acid, sulfurdioxide or phosphoric acid, they undergo a three-step transformation resulting in a mixture of ammoniumpentaborate, the corresponding alkali metal and/or alkaline earth metal salt(s): sulfate, sulfite or hydrophosphate and ammonia (Equation 1). Alternately, tetraborates undergo the same three-step reactions upon their treatment with equimolar amounts of ammoniumsulfate, ammoniumsulfite or diammoniumhydrogenphosphate, while the liberated ammonia can be boiled off with distilling water. This application deals with the discovery of highly effective, permanent flame retardant compositions which also possess excellent antismoldering, noncorrosive and fungal resistant properties when properly applied on cellulosic fibers, cellulose-lignin fiber insulation materials.

  当碱金属和/或碱土金属四硼酸盐在水悬浮液中经过适当的氨和硫酸、二氧化硫或磷酸处理时，它们经历了三步转化，形成了氨基五硼酸盐、相应的碱金属和/或碱土金属盐：硫酸盐、亚硫酸盐或磷酸盐和氨（方程式1）。或者，四硼酸盐在与等摩尔量的硫酸铵、亚硫酸铵或双氢氧磷酸铵处理时也会经历同样的三步反应，而释放的氨可以用蒸馏水蒸发掉。本申请涉及发现了高效的、永久的阻燃组合物，当正确应用于纤维素纤维、纤维素-木质素纤维绝缘材料时，还具有优异的防烟、不腐蚀和抗真菌性能。
• Process for removing sulfur from waste waters containing sulfuric acid
  申请人：Institut Francais du Petrole

  公开号：US04039649A1

  公开（公告）日：1977-08-02

  Process for recovering sulfur from waste waters containing sulfuric acid, comprising reacting in a first step, the waste water with an aqueous solution of ammonium sulfite, separating the formed sulfur dioxide from the solution, reacting the resulting solution in a second step with calcium oxide to form calcium sulfate and an aqueous ammonia solution, vaporizing ammonia therefrom, reducing the calcium sulfate by means of carbon to form calcium oxide and sulfur dioxide, contacting said vaporized ammonia with said sulfur dioxide and with water, thereby forming an aqueous solution of ammonium sulfite, which is joined to that used in the first step and recycling at least a part of the calcium oxide obtained by reduction of the calcium sulfate to the second step.

  从含硫酸的废水中回收硫的过程，包括以下步骤：第一步，将废水与硫代硫酸铵水溶液反应，将生成的二氧化硫从溶液中分离出来；第二步，将所得的溶液与氧化钙反应，形成硫酸钙和氨水溶液，从中蒸发氨气，用碳还原硫酸钙形成氧化钙和二氧化硫，将蒸发的氨气与二氧化硫和水接触，从而形成硫代硫酸铵水溶液，将其与第一步使用的溶液混合，同时至少回收部分通过还原硫酸钙所得的氧化钙用于第二步。
• Process for purifying waste water containing ammonium sulfate
  申请人：Institut Francais du Petrole

  公开号：US04058591A1

  公开（公告）日：1977-11-15

  This process for purifying waste-water containing ammonium sulfate comprises reacting said waste-water with calcium oxide, calcium sulfide and ammonium sulfite; roasting the resulting precipitate to regenerate calcium oxide and calcium sulfide; and reacting sulfur dioxide with hydrogen sulfide obtained in a prior step to yield sulfur.

  这个净化含硫酸铵废水的过程包括将废水与氧化钙、硫化钙和亚硫酸铵反应；将产生的沉淀烧结以再生氧化钙和硫化钙；并将在先前步骤中获得的硫化氢与二氧化硫反应以产生硫。