7-imino-N,N,8-trimethylphenothiazin-3-amine;hydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: 7-imino-N,N,8-trimethylphenothiazin-3-amine;hydrochloride
• 化学式: C15H16ClN3S
• 分子量: 305.8
• InChiKey: GEDVVYWLPUPJJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.67
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  66.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 甲苯胺蓝 以 甲醇 为溶剂， 反应 48.67h， 生成 7-imino-N,N,8-trimethylphenothiazin-3-amine;hydrochloride
  参考文献：
  名称：

  MATERIALS AND METHODS FOR CONTROLLING VASCULOGENESIS FROM ENDOTHELIAL COLONY FORMING CELLS

  摘要：

  本文披露了使用胶原基质和内皮细胞集落形成细胞（ECFC）的构建块来控制血管生成的材料和方法。这些构建块可以通过分离可溶性I型胶原酸来获得。含有单体和/或寡聚体的构建块可以以所需比例重新组合，以改变基质微环境并影响ECFC行为。

  公开号：

  US20140193473A1

文献信息

• Nitric Oxide Releasing Prodrugs of Therapeutic Agents
  申请人：SATYAM Apparao

  公开号：US20110263526A1

  公开（公告）日：2011-10-27

  The present invention relates to nitric oxide releasing prodrugs of known drugs or therapeutic agents which are represented herein as compounds of formula (I) wherein the drugs or therapeutic agents contain one or more functional groups independently selected from a carboxylic acid, an amino, a hydroxyl and a sulfhydryl group. The invention also relates to processes for the preparation of the nitric oxide releasing prodrugs (the compounds of formula (I)), to pharmaceutical compositions containing them and to methods of using the prodrugs.

  本发明涉及已知药物或治疗剂的一氧化氮释放前药，其在此处表示为式(I)的化合物，其中药物或治疗剂包含一个或多个功能基团，独立地选自羧酸、氨基、羟基和巯基。该发明还涉及制备一氧化氮释放前药（式(I)的化合物）的方法，含有它们的药物组合物以及使用这些前药的方法。
• Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor
  申请人：Bass Stephen

  公开号：US20060074257A1

  公开（公告）日：2006-04-06

  This invention relates to a method for inhibiting polymerization of (meth)acrylic acid and its esters using a polymerization inhibitor which comprises at least one reduced halide-content azine dye-based compound. A process for producing reduced halide-content azine dye-based compounds using ion exchange resin technology is also provided.

  这项发明涉及一种使用至少一种含有还原卤化物的偶氮染料化合物作为聚合抑制剂来抑制（甲基）丙烯酸及其酯的聚合的方法。还提供了一种利用离子交换树脂技术生产含有还原卤化物的偶氮染料化合物的方法。
• Diagnostic/therapeutic agents
  申请人：Klaveness Jo

  公开号：US20050002865A1

  公开（公告）日：2005-01-06

  Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, comprising a suspension in an aqueous carrier liquid of a reporter comprising gas-containing or gas-generating material, said agent being capable of forming at least two types of binding pairs with a target.

  可定位的诊断和/或治疗活性剂，例如超声对比剂，包括悬浮在水载体液中的报告物，该报告物包含含气体或生成气体的材料，该剂能够与目标形成至少两种结合对。
• Hydrogen peroxide and peracetic acid indicators and methods
  申请人：Read M. David

  公开号：US20070134797A1

  公开（公告）日：2007-06-14

  The present invention provides a hydrogen peroxide indicator and a peracetic acid indicator that include a substrate on which is disposed an indicator composition that includes at least one of a select group of colorants and a transition metal salt. As a result of exposure to hydrogen peroxide and/or peracetic acid, the colorants change color, and even become colorless, thereby providing an indication of the presence of hydrogen peroxide and/or peracetic acid.

  本发明提供了一种过氧化氢指示剂和过乙酸指示剂，包括基质，上面放置有指示剂组合物，其中包括一种选择的颜料组和过渡金属盐。由于暴露于过氧化氢和/或过乙酸，颜料会改变颜色，甚至变为无色，从而指示出过氧化氢和/或过乙酸的存在。
• METHOD FOR INHIBITING POLYMERIZATION OF (METH) ACRYLIC ACID AND ITS ESTERS USING AN INHIBITOR AND A PROCESS FOR MAKING A COMPOUND USEFUL AS SUCH AN INHIBITOR
  申请人：Bass Stephen

  公开号：US20070197785A1

  公开（公告）日：2007-08-23

  This invention relates to a method for inhibiting polymerization of (meth)acrylic acid and its esters using a polymerization inhibitor which comprises at least one reduced halide-content azine dye-based compound. A process for producing reduced halide-content azine dye-based compounds using ion exchange resin technology is also provided.

  本发明涉及使用至少含有一种还原卤化物含量的偶氮染料化合物的聚合抑制剂来抑制（甲基）丙烯酸及其酯的聚合的方法。本发明还提供了使用离子交换树脂技术生产含有还原卤化物含量的偶氮染料化合物的方法。

表征谱图