2-(4-methoxyphenyl)-6-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | 1334951-32-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酰胺类
• 英文名称: 2-(4-methoxyphenyl)-6-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
• 英文别名: 2-(4-Methoxyphenyl)-6-(1,4,7,10-tetraoxa-13-azacyclopentadec-13-yl)benzo[de]isoquinoline-1,3-dione；2-(4-methoxyphenyl)-6-(1,4,7,10-tetraoxa-13-azacyclopentadec-13-yl)benzo[de]isoquinoline-1,3-dione
• CAS: 1334951-32-4
• 化学式: C₂₉H₃₂N₂O₇
• 分子量: 520.582
• InChiKey: ONQUYVLJSLRTMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  38
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  86.8
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  6-bromo-2-(4-methoxyphenyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione 、 氮杂-15-冠醚-5 在 吡啶 作用下， 反应 15.0h， 以53%的产率得到2-(4-methoxyphenyl)-6-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
  参考文献：
  名称：

  A rapid Hg2+ sensor based on aza-15-crown-5 ether functionalized 1,8-naphthalimide

  摘要：

  A new 1,8-naphthalimide derivative bearing an aza-15-crown-5 macrocycle (1) has been synthesized as a chemosensor for Hg2+ by a two-step reaction. The sensor shows selectivity to Hg2+ over 11 other metal cations in aqueous media. Upon addition of Hg2+, the fluorescence emission of the sensor at 537 nm is significantly quenched along with 22 nm blue-shift that makes this compound a useful sensor for Hg2+ measurement. Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2011.07.056

文献信息

• A rapid Hg2+ sensor based on aza-15-crown-5 ether functionalized 1,8-naphthalimide
  作者：Chen Hou、Alysha M. Urbanec、Haishi Cao

  DOI：10.1016/j.tetlet.2011.07.056

  日期：2011.9

  A new 1,8-naphthalimide derivative bearing an aza-15-crown-5 macrocycle (1) has been synthesized as a chemosensor for Hg2+ by a two-step reaction. The sensor shows selectivity to Hg2+ over 11 other metal cations in aqueous media. Upon addition of Hg2+, the fluorescence emission of the sensor at 537 nm is significantly quenched along with 22 nm blue-shift that makes this compound a useful sensor for Hg2+ measurement. Published by Elsevier Ltd.