4-chloro-3-methyl-hexane | 110505-53-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 4-chloro-3-methyl-hexane
• 英文别名: 4-Chlor-3-methyl-hexan；3-Chloro-4-methylhexane
• CAS: 110505-53-8
• 化学式: C₇H₁₅Cl
• 分子量: 134.649
• InChiKey: NZMZLLXENBPQGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氯化亚砜 、 Petroleum ether 作用下， 生成 4-chloro-3-methyl-hexane
  参考文献：
  名称：

  Duveen; Kenyon, Bulletin de la Societe Chimique de France, 1938, vol. <5>5, p. 1125

  摘要：

  DOI：

文献信息

• [EN] INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2<br/>[FR] DÉRIVÉS D'INDAZOLE UTILES EN TANT QU'INHIBITEURS DE LA DIACYLGLYCÉRIDE O-ACYLTRANSFÉRASE 2
  申请人：MERCK SHARP & DOHME

  公开号：WO2018093696A1

  公开（公告）日：2018-05-24

  The present invention relates to a compound represented by formula I': and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors of diacylglyceride O-acyltransferase 2 ("DGAT2") and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.

  本发明涉及一种由公式I'表示的化合物及其药学上可接受的盐。公式I的化合物是二酰甘油O-酰基转移酶2（“DGAT2”）的抑制剂，可能在治疗、预防和抑制由DGAT2介导的疾病方面有用。本发明的化合物可能在治疗肝脂肪变性、糖尿病、肥胖、高脂血症、高胆固醇血症、动脉粥样硬化、心肾疾病（如慢性肾脏疾病和心力衰竭）以及相关疾病和症状的治疗中有用。
• Phthalocyanine compounds and optical recording media comprising them
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0719839A2

  公开（公告）日：1996-07-03

  A near infrared light-absorbing dye comprising phthalocyanine compounds represented by the following formula (2): wherein in formula (2), M is two hydrogen atoms, a divalent metallic atom, a trivalent monosubstituted metallic atom, a tetravalent disubstituted metallic atom or an oxymetal atom, and L1, L2, L3 and L4 are each independently formula (a) or (b),    in the formula (a) or (b), R1 and R3 are each a substituted or unsubstituted alkyl group, and R2 is a straight chain or branched halogenated alkyl or alkenyl group having 3 to 10 carbon atoms, X is a chlorine, bromine or iodine atom, and m is an integer of 1 to 12, provided that formula (2) represents a mixture of L1 = L2 = L3= L4 = formula (a), L1 = L2 = L4 = formula (a) and L3 = formula (b), L1 = L4 = formula (a) and L2 = L3 = formula (b), L1 = L3 = formula (a) and L2 = L4 = formula (b), L1 = formula (a) and L2 = L3 = L4 = formula (b), and L1 = L2 = L3 = L4 = formula (b), and an optical recording medium comprising the phthalocyanine mixture.

  一种近红外吸光染料，由下式（2）所代表的酞菁化合物组成： 其中，在式 (2) 中，M 是两个氢原子、二价金属原子、三价单取代金属原子、四价二取代金属原子或氧金属原子，L1、L2、L3 和 L4 分别独立地为式 (a) 或 (b)、 在式 (a) 或 (b) 中，R1 和 R3 分别是取代或未取代的烷基，R2 是具有 3 至 10 个碳原子的直链或支链卤代烷基或烯基、 X是氯、溴或碘原子，m是1至12的整数，条件是式(2)代表L1=L2=L3= L4=式(a)、L1=L2=L4=式(a)和L3=式(b)的混合物、L1 = L4 = 式（a）和 L2 = L3 = 式（b），L1 = L3 = 式（a）和 L2 = L4 = 式（b），L1 = 式（a）和 L2 = L3 = L4 = 式（b），以及 L1 = L2 = L3 = L4 = 式（b）、 以及包含酞菁混合物的光学记录介质。
• Electrophotographic photosensitive member, and electrophotgraphic apparatus and process cartridge which make use of the same
  申请人：Canon Kabushiki Kaisha

  公开号：EP1947515A2

  公开（公告）日：2008-07-23

  This invention relates to an electrophotographic photosensitive member having a support and a photosensitive layer. In the electrophotographic photosensitive member having a support and a photosensitive layer, which electrophotographic photosensitive member makes use of, as writing light, a semiconductor laser light ray having a wavelength of from 380 to 500 nm, the photosensitive layer contains a bisazo pigment represented by the following Formula (1): wherein A1, A2 and A3 may be the same or different, and each independently represent a saturated or unsaturated aliphatic hydrocarbon group which may have a substituent, an aromatic hydrocarbon ring group which may have a substituent, a heterocyclic ring group which may have a substituent, or a carbonyl group; R1 and R2 may be the same or different, and each independently represent an alkyl.group which may have a substituent, an aryl group which may have a substituent, or a halogen atom; R3, R4, R5 and R6 may be the same or different, and each independently represent a hydrogen atom, an alkyl group which may have a substituent, an aryl group which may have a substituent, a heterocyclic ring group which may have a substituent, or an aralkyl group which may have a substituent, provided that R3 and R4, and R5 and R6, may each form a cyclic amino group via the nitrogen atom in the formula; Z1 and Z2 each independently represent an oxygen atom or a sulfur atom; m1 and m2 each represent an integer of 0 to 4; and n1, n2 and n3 each independently represent. 0 or 1.

  本发明涉及一种具有支架和感光层的电子照相感光元件。 在这种具有支架和感光层的电子照相感光构件中，该电子照相感光构件利用波长为 380 至 500 纳米的半导体激光光线作为书写光，感光层含有由下式（1）表示的双氮颜料： 其中 A1、A2 和 A3 可以相同或不同，各自独立地代表饱和或不饱和脂肪烃基团（可以有取代基）、芳香烃环基团（可以有取代基）、杂环环基团（可以有取代基）或羰基；R1 和 R2 可以相同或不同，各自独立地代表烷基。R3、R4、R5 和 R6 可以相同或不同，且各自独立地代表氢原子、可 以具有取代基的烷基、可以具有取代基的芳基、可以具有取代基的杂环基团或可以 具有取代基的芳烷基，条件是 R3 和 R4 以及 R5 和 R6 可以各自通过式中的氮原子形 成环状氨基；Z1和Z2各自独立地代表氧原子或硫原子； m1和m2各自独立地代表0至4的整数； n1、n2和n3各自独立地代表。0 或 1。
• US5693396A
  申请人：——

  公开号：US5693396A

  公开（公告）日：1997-12-02
• [EN] NEW INHIBITORS OF BONE RESORPTION<br/>[FR] NOUVEAUX INHIBITEURS DE RÉSORPTION OSSEUSE
  申请人：CENTRE NAT RECH SCIENT

  公开号：WO2019197659A1

  公开（公告）日：2019-10-17

  The invention relates to a compound of formula (I): and its use as drug, in particular for use in prevention and/or treatment of disease- associated bone loss, preferably selected in the group consisting of bone metastases, multiple myeloma, osteoporosis, osteopenia due to bone metastases, osteogenesis imperfecta, periarticular erosions in rheumatoid arthritis, primary hyperparathyroidism, hypercalcemia of malignancy, Paget's disease of bone, periodontal disease, immobilization induced osteopenia, and glucocorticoid treatment.