cholest-5-en-3β-yl N-phenylthionocarbamate | 35602-10-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: cholest-5-en-3β-yl N-phenylthionocarbamate
• 英文别名: 3β-phenylthiocarbamoyloxy-cholest-5-ene；Phenyl-thiocarbamidsaeure-O-cholesterylester；O-Phenylthiocarbamoyl-cholesterin；3β-Phenylthiocarbamoyloxy-cholest-5-en；O-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]] N-phenylcarbamothioate
• CAS: 35602-10-9
• 化学式: C₃₄H₅₁NOS
• 分子量: 521.851
• InChiKey: KZGQLQOCEZBFOY-LLHZKFLPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  37
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  53.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  cholest-5-en-3β-yl N-phenylthionocarbamate 在 三乙基硅烷 、 过氧化氢苯甲酰 作用下， 以 苯 为溶剂， 以65%的产率得到5-胆甾烯
  参考文献：
  名称：

  Addition reaction and deoxygenation of alcohols using isothiocyanates and triethylsilane-DTBP

  摘要：

  Alcohols were found to be deoxygenated through treatment with isothiocyanates giving thionocarbamates, followed by reduction with triethylsilane.

  DOI：

  10.1016/s0040-4039(00)79216-1
• 作为产物：
  描述：

  胆固醇 、 硫代异氰酸苯酯 在 三丁基氧化锡 作用下， 生成 cholest-5-en-3β-yl N-phenylthionocarbamate
  参考文献：
  名称：

  Addition reaction and deoxygenation of alcohols using isothiocyanates and triethylsilane-DTBP

  摘要：

  Alcohols were found to be deoxygenated through treatment with isothiocyanates giving thionocarbamates, followed by reduction with triethylsilane.

  DOI：

  10.1016/s0040-4039(00)79216-1

文献信息

• Addition reaction and deoxygenation of alcohols using isothiocyanates and triethylsilane-DTBP
  作者：Kozaburo Nishiyama、Makoto Oba、Masahiko Oshimi、Tunetoshi Sugawara、Ryuichi Ueno

  DOI：10.1016/s0040-4039(00)79216-1

  日期：1993.6

  Alcohols were found to be deoxygenated through treatment with isothiocyanates giving thionocarbamates, followed by reduction with triethylsilane.