isoquinolinium perchlorate | 57147-10-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: isoquinolinium perchlorate
• 英文别名: isoquinolin-2-ium;perchlorate
• CAS: 57147-10-1
• 化学式: C₉H₇N*ClHO₄
• 分子量: 229.62
• InChiKey: IFSTXIFJFABXJL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.89
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  84.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  isoquinolinium perchlorate 以 乙腈 为溶剂， 生成 2-Benzoyl-isoquinolinium; perchlorate
  参考文献：
  名称：

  Sheinkman, A. K.; Skorobogatova, Z. M.; Chmilenko, T. S., Doklady Chemistry, 1982, vol. 267, p. 428 - 431

  摘要：

  DOI：
• 作为产物：
  描述：

  N-aminoisoquinolinium perchlorate 在 氧气 、 氧化亚氮 作用下， 以 乙腈 为溶剂， 反应 0.08h， 以92%的产率得到isoquinolinium perchlorate
  参考文献：
  名称：

  Radical Scavenging by N -Aminoazaaromatics

  摘要：

  N-Aminoazaaromatics were found to react with nitric oxide in the presence of oxygen to afford deaminated products in high yields. The reaction proceeded almost instantaneously in various solvents including water, and one to two equivalent of NO was consumed depending upon the amount of oxygen coexisted, and 1 equivalent of N2O was released in the reaction. In addition, N-aminoazoles were deaminated by potassium superoxide to give parent azoles in good yields. Two equivalents of superoxide was consumed, and about half equivalents of both nitrite and nitrate ion were released. The results demonstrated that N-aminoazoles have ability to protect the biological system against the oxidation promoted by radicals such as nitrogen oxides and superoxide. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0968-0896(00)00118-8

文献信息

• Biofilm-Inhibiting Effect and Anti-Infective Activity of N,C- Linked Arylisoquinolines and the Use Thereof
  申请人：Bringmann Gerhard

  公开号：US20100286198A1

  公开（公告）日：2010-11-11

  Anti-infective and biofilm-inhibiting activities of aryl isoquinoline-derivatives of the general formulae 1 to 3 are described.

  描述了通式1到3的芳基异喹啉衍生物的抗感染和抑制生物膜活性。
• Photographic compositions and elements containing benzo[a]quinolizinium
  申请人：Eastman Kodak Company

  公开号：US04108667A1

  公开（公告）日：1978-08-22

  The invention relates to methine dyes and photographic silver halide compositions and film elements comprising methine dyes which contain 9,9a-dihydropyrido-[1,2-a]indolium nuclei, benzo[a]quinolizinium nuclei or 6,7-dihydrobenzo[a]quinolizinium nuclei.

  本发明涉及甲烯染料、含有甲烯染料的摄影银卤化物组合物和胶片元素，所述甲烯染料包含9,9a-二氢吡啶并[1,2-a]吲哚核、苯并[a]喹啉核或6,7-二氢苯并[a]喹啉核。
• Substituted heterocyclylisoquinolinium salts and compositions and method
  申请人：Sterling Winthrop Inc.

  公开号：US05569655A1

  公开（公告）日：1996-10-29

  Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.

  替代杂环异喹啉盐，含有它们的药物组合物以及利用它们治疗或预防神经退行性疾病或神经毒性损伤的方法。
• Reaction of pyridines with epichlorohydrin
  作者：V. S. Garkusha-Bozhko、O. P. Shvaika

  DOI：10.1007/bf00497217

  日期：1990.4
• Reactions of 1,2-Epoxides with Salts of Organic Bases. I. Styrene Oxide
  作者：L. Carroll. King、Neil W. Berst、F. N. Hayes

  DOI：10.1021/ja01178a070

  日期：1949.10