5α-Pregnan-11,20-dion | 2402-13-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5α-Pregnan-11,20-dion
• 英文别名: 5a-Pregnan-11,20-dion；(5R,8S,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
• CAS: 2402-13-3
• 化学式: C₂₁H₃₂O₂
• 分子量: 316.484
• InChiKey: IFHKDUOXEKUXGA-JHGMSEHPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5α-Pregnan-11,20-dion 生成 11-oxo-pregn-17(20)ξ-en-21-oic acid methyl ester
  参考文献：
  名称：

  11-oxygenated 17alpha, 21-dihydroxyallopregnan-20-one and esters thereof

  摘要：

  公开号：

  US02868808A1
• 作为产物：
  描述：

  3-benzylsulfanyl-pregna-3,5-diene-11,20-dione 在 palladium on activated charcoal 、 镍 、 乙酸乙酯 、 丙酮 作用下， 生成 5α-Pregnan-11,20-dion
  参考文献：
  名称：

  3-deoxy-11,17-oxygenated-androstanes

  摘要：

  公开号：

  US02881188A1

文献信息

• Phosphate derivatives of pharmaceutical products
  申请人：West Michael Simon

  公开号：US20070042999A1

  公开（公告）日：2007-02-22

  According to the invention, there is provided a complex of a pharmaceutical compound selected from the group consisting of opioids, hormones, anaethetics and chemotherapeutic agents comprising the reaction product of: (a) one or more phosphate derivatives of one or more opioids, steroid hormones, thyroid hormones, anaesthetics or chemotherapeutic agents having a phenolic, primary alcohol, secondary alcohol or tertiary hydroxyl group; and (b) a complexing agent selected from the group comprising amphoteric surfactants, cationic surfactants, amino acids having nitrogen functional groups and proteins rich in these amino acids.
• 3-deoxy-11,17-oxygenated-androstanes
  申请人：UPJOHN CO

  公开号：US02881188A1

  公开（公告）日：1959-04-07
• 11-oxygenated 17alpha, 21-dihydroxyallopregnan-20-one and esters thereof
  申请人：UPJOHN CO

  公开号：US02868808A1

  公开（公告）日：1959-01-13