Acetic acid 3''-benzyloxy-3',2''-dihydroxy-2,2'-dimethoxy-[1,1';4',1'']ternaphthalen-3-yl ester | 300533-66-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Acetic acid 3''-benzyloxy-3',2''-dihydroxy-2,2'-dimethoxy-[1,1';4',1'']ternaphthalen-3-yl ester
• 英文别名: [4-[3-hydroxy-4-(2-hydroxy-3-phenylmethoxynaphthalen-1-yl)-2-methoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate
• CAS: 300533-66-8
• 化学式: C₄₁H₃₂O₇
• 分子量: 636.701
• InChiKey: KLMDRJSRNVTURJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.4
• 重原子数：
  48
• 可旋转键数：
  9
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  Acetic acid 3''-benzyloxy-3',2''-dihydroxy-2,2'-dimethoxy-[1,1';4',1'']ternaphthalen-3-yl ester 在 palladium on activated charcoal 氢气 作用下， 生成 Acetic acid 3''-hydroxy-2,2',3',2''-tetramethoxy-[1,1';4',1'']ternaphthalen-3-yl ester
  参考文献：
  名称：

  Synthesis of Configurationally Defined Sexi- and Octinaphthalene Derivatives

  摘要：

  [GRAPHICS]Configurationally defined optically active octinaphthalenes were synthesized using the oxidative coupling of optically active quaternaphthalenes with a 2-hydroxynaphthol moiety as a key reaction. The absolute configuration was determined by comparison with products of [6 + 2] coupling.

  DOI：

  10.1021/ol006843c
• 作为产物：
  描述：

  Acetic acid 3'-acetoxy-2,2'-dimethoxy-[1,1']binaphthalenyl-3-yl ester 在 N-乙基苯胺 、 copper dichloride 作用下， 以 甲醇 、 二氯甲烷 、 异丙醚 为溶剂， 反应 44.0h， 生成 Acetic acid 3''-benzyloxy-3',2''-dihydroxy-2,2'-dimethoxy-[1,1';4',1'']ternaphthalen-3-yl ester
  参考文献：
  名称：

  六羟基叔和八羟基季萘衍生物的制备和绝对构型

  摘要：

  立体化学定义的S-四羟基双萘衍生物的氧化偶联反应得到S，S，S和S，R，S构型的季萘的两种非对映异构体的可分离混合物，其立体结构通过通过对苯二甲酸以及其他方法的化学转化得到证实X射线结构分析。相应的非对映异构体的CD光谱表明了整个轴上的立体化学。

  DOI：

  10.1016/0957-4166(96)00270-4

文献信息

• Recognition of the chain length of α,ω-diamines by a meso-ternaphthalene derivative with two crown ethers
  作者：Kazunori Tsubaki、Hiroyuki Tanaka、Takumi Furuta、Takayoshi Kinoshita、Kaoru Fuji

  DOI：10.1016/s0040-4039(00)01018-2

  日期：2000.8

  A new ditopic receptor 2 consisting of a meso-ternaphthalene backbone and two crown rings has been shown to selectively complex and transfer dipicrate of 1,9-diaminononane and 1,10-diaminodecane from aqueous solution into the organic phase.

  已经显示了一种新的二位受体2，它由内-间萘骨架和两个冠环组成，可以选择性地将1,9-二氨基壬烷和1,10-二氨基癸烷的二尖晶石络合物从水溶液中转移到有机相中。
• Use of meso-ternaphthalene derivatives: linear recognition of the α,ω-diamines by homoditopic receptors
  作者：Kazunori Tsubaki、Hiroyuki Tanaka、Takumi Furuta、Kiyoshi Tanaka、Takayoshi Kinoshita、Kaoru Fuji

  DOI：10.1016/s0040-4020(02)00547-1

  日期：2002.7

  The new ditopic receptors 1-3 consisting of a meso-ternaphthalene backbone and two crown ether rings have been synthesized. Hosts 2 and 3 have been shown to selectively complex and transfer the dipicrates, 1,9-diaminononane and 1,10-diaminodecane, from aqueous solution into the organic phase. (C) 2002 Elsevier Science Ltd. All rights reserved.
• Configurationally defined sexi- and octinaphthalene derivatives: synthesis and optical properties
  作者：Takumi Furuta、Kiyoshi Tanaka、Kazunori Tsubaki、Kaoru Fuji

  DOI：10.1016/j.tet.2004.03.055

  日期：2004.5

  The copper mediated oxidative coupling of optically active quaternaphthalenes having a 2-hydroxynaphthyl moiety gave configurationally defined optically active octinaphthalenes. The absolute configuration was determined by comparison with products of [6+2] coupling. The CD spectra of bi-, ter-, quater-, sexi- and octinaphthalenes suggested that the absolute configuration of the chiral axis could be deduced from the intensity of their Cotton effects. (C) 2004 Published by Elsevier Ltd.