1-(5-(N-allyl-N-methylamino)fur-2-yl)but-3-en-1-ol | 1144506-70-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-(5-(N-allyl-N-methylamino)fur-2-yl)but-3-en-1-ol
• 英文别名: 1-[5-[Methyl(prop-2-enyl)amino]furan-2-yl]but-3-en-1-ol；1-[5-[methyl(prop-2-enyl)amino]furan-2-yl]but-3-en-1-ol
• CAS: 1144506-70-6
• 化学式: C₁₂H₁₇NO₂
• 分子量: 207.272
• InChiKey: GTARTUYUTFLCNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  36.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-(N-allyl-N-methyl)amino-2-furancarboxaldehyde 、 烯丙基溴化镁 以 四氢呋喃 为溶剂， 生成 1-(5-(N-allyl-N-methylamino)fur-2-yl)but-3-en-1-ol
  参考文献：
  名称：

  First Entry to [4+2] Cycloadditions Involving 5-Amino-2-furanmethanols

  摘要：

  The preparation of new 5-amino-2-furanmethanols bearing various amino and primary or secondary alcohol groups is described. The structures of 5-amino-2-furanmethanols as dienes are consistent with (1)H NMR data and cyloadditions of them allows the selective synthesis of tetrasubstituted aminobenzylic alcohols, amino phenols or lactones through Diels-Alder reactions.

  DOI：

  10.3987/com-08-11556

文献信息

• First Entry to [4+2] Cycloadditions Involving 5-Amino-2-furanmethanols
  作者：Sylvain Marque、Damien Prim、Raouf Medimagh、Saber Chatti

  DOI：10.3987/com-08-11556

  日期：——

  The preparation of new 5-amino-2-furanmethanols bearing various amino and primary or secondary alcohol groups is described. The structures of 5-amino-2-furanmethanols as dienes are consistent with (1)H NMR data and cyloadditions of them allows the selective synthesis of tetrasubstituted aminobenzylic alcohols, amino phenols or lactones through Diels-Alder reactions.