1,6-Diacetylglykoluril | 55367-79-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: 1,6-Diacetylglykoluril
• 英文别名: 1,6-diacetylglycoluril；1,6-diacetyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dione；1,6-Diacetyltetrahydroimidazo[4,5-d]imidazole-2,5(1h,3h)-dione；3,4-diacetyl-1,3a,6,6a-tetrahydroimidazo[4,5-d]imidazole-2,5-dione
• CAS: 55367-79-8
• 化学式: C₈H₁₀N₄O₄
• mdl: MFCD05025236
• 分子量: 226.192
• InChiKey: NDMUOHYEWAXJQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  98.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  溴甲苯 、 1,6-Diacetylglykoluril 在 potassium carbonate 作用下， 以 二甲基亚砜 为溶剂， 反应 17.0h， 生成
  参考文献：
  名称：

  1,6-Dibenzylglycoluril for synthesis of deprotected glycoluril dimer

  摘要：

  1,6-Dibenzylglycoluril is not accessible via classical condensation reaction between substituted urea and glyoxal. In this paper 1,6-dibenzylglycoluril was successfully prepared by alkylation of 1,6-diacetylglycoluril with benzylbromide for the first time. 1,6-Dibenzylglycoluril reacted with formaldehyde to give tetrabenzylglycoluril dimer. Deprotection of this dimer and the previously reported o-xylyleneglycoluril dimer was achieved by dissolving metal reduction, whereas propyleneglycoluril dimer was deprotected by action of potassium persulfate. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.08.097
• 作为产物：
  描述：

  四乙酰甘脲 生成 1,6-Diacetylglykoluril
  参考文献：
  名称：

  HASE C.; KUEHLING D., J. LIEBIGS ANN. CHEM. , 1975, NO 1, 95-102

  摘要：

  DOI：

文献信息

• 1,6-Dibenzylglycoluril for synthesis of deprotected glycoluril dimer
  作者：Marek Stancl、Muhammad S.A. Khan、Vladimir Sindelar

  DOI：10.1016/j.tet.2011.08.097

  日期：2011.11

  1,6-Dibenzylglycoluril is not accessible via classical condensation reaction between substituted urea and glyoxal. In this paper 1,6-dibenzylglycoluril was successfully prepared by alkylation of 1,6-diacetylglycoluril with benzylbromide for the first time. 1,6-Dibenzylglycoluril reacted with formaldehyde to give tetrabenzylglycoluril dimer. Deprotection of this dimer and the previously reported o-xylyleneglycoluril dimer was achieved by dissolving metal reduction, whereas propyleneglycoluril dimer was deprotected by action of potassium persulfate. (C) 2011 Elsevier Ltd. All rights reserved.
• HASE C.; KUEHLING D., J. LIEBIGS ANN. CHEM. <JLAC-BF>, 1975, NO 1, 95-102
  作者：HASE C.、 KUEHLING D.

  DOI：——

  日期：——