Furan-2-yl-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-methanol | 863479-87-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Furan-2-yl-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-methanol
• 英文别名: Furan-2-yl-(6-methoxy-3,4-dihydronaphthalen-1-yl)methanol
• CAS: 863479-87-2
• 化学式: C₁₆H₁₆O₃
• 分子量: 256.301
• InChiKey: BTYNXLYRBRLRTQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  42.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Furan-2-yl-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-methanol 在 三溴化磷 作用下， 以 苯 为溶剂， 反应 0.1h， 以49%的产率得到2-(6-methoxynaphthalen-1-ylmethyl)furan
  参考文献：
  名称：

  Convenient phosphorus tribromide induced syntheses of substituted 1-arylmethylnaphthalenes from 1-tetralone derivatives

  摘要：

  A series of 1-arylmethylnaphthalenes 7a-g and I I have been synthesized conveniently in good yields at room temperature through phosphorus tribromide induced aromatization of 1-aryl-[3,4]-dihydronaphthyl-methanols 6a-g and 10, which were obtained from 1-tetralone derivatives. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.06.016
• 作为产物：
  描述：

  6-甲氧基-1-萘满酮 在 正丁基锂 、 三溴化磷 作用下， 以 四氢呋喃 、 苯 为溶剂， 生成 Furan-2-yl-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-methanol
  参考文献：
  名称：

  Convenient phosphorus tribromide induced syntheses of substituted 1-arylmethylnaphthalenes from 1-tetralone derivatives

  摘要：

  A series of 1-arylmethylnaphthalenes 7a-g and I I have been synthesized conveniently in good yields at room temperature through phosphorus tribromide induced aromatization of 1-aryl-[3,4]-dihydronaphthyl-methanols 6a-g and 10, which were obtained from 1-tetralone derivatives. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.06.016

文献信息

• Convenient phosphorus tribromide induced syntheses of substituted 1-arylmethylnaphthalenes from 1-tetralone derivatives
  作者：Shagufta、Resmi Raghunandan、Prakas R. Maulik、Gautam Panda

  DOI：10.1016/j.tetlet.2005.06.016

  日期：2005.8

  A series of 1-arylmethylnaphthalenes 7a-g and I I have been synthesized conveniently in good yields at room temperature through phosphorus tribromide induced aromatization of 1-aryl-[3,4]-dihydronaphthyl-methanols 6a-g and 10, which were obtained from 1-tetralone derivatives. (c) 2005 Elsevier Ltd. All rights reserved.