1,3,8,10-tetraoxa-cyclotetradecane-2,9-dione | 87719-16-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: 1,3,8,10-tetraoxa-cyclotetradecane-2,9-dione
• 英文别名: 1,3,8,10-Tetraoxa-cyclotetradecan-2,9-dion；1,3,8,10-Tetraoxacyclotetradecane-2,9-dione
• CAS: 87719-16-2
• 化学式: C₁₀H₁₆O₆
• 分子量: 232.233
• InChiKey: KGBCZKSFVVEERO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  1,4-丁二醇 、 碳酸二乙酯 在 乙醇 、 sodium ethanolate 、 甲苯 作用下， 生成 1,3,8,10-tetraoxa-cyclotetradecane-2,9-dione
  参考文献：
  名称：

  Cyclic Dienes. XVI. 9,10-Dimethylene-1,7-dioxacyclohendecane-2,6-dione, A Cyclic Ester from 2,3-Di-(hydroxymethyl)-1,3-butadiene^1,2

  摘要：

  DOI：

  10.1021/ja01591a071

文献信息

• STRONG REVERSIBLE HYDROGELS
  申请人：BAUGHMAN Trayvis Wayne

  公开号：US20080260795A1

  公开（公告）日：2008-10-23

  The present invention relates to improved hydrogel materials using water gellants that are comprised of polymer backbones P to which hydrogen bonding 4H-units are covalently attached via a hydrophobic linker L. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and function and are especially suitable for biomedical applications.

  本发明涉及改进的水凝胶材料，使用由聚合物骨架P组成的水凝胶剂，通过疏水连接剂L共价连接到其中的氢键4H单元。可选地，水凝胶还包含其他成分或添加剂。这些新的可逆水凝胶可以轻松地在机械性能和功能上进行微调，并且特别适用于生物医学应用。
• Strong reversible hydrogels
  申请人：SupraPolix B.V.

  公开号：EP1972661A1

  公开（公告）日：2008-09-24

  The present invention relates to improved hydrogel materials using water gellants that are comprised of polymer backbones P to which hydrogen bonding 4H-units are covalently attached via a hydrophobic linker L. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and function and are especially suitable for biomedical applications.

  本发明涉及使用水胶凝剂的改进型水凝胶材料，该材料由聚合物骨架 P 组成，氢键 4H 单元通过疏水连接剂 L 共价连接到聚合物骨架 P 上。这些新型可逆水凝胶可以很容易地对其机械性能和功能进行微调，尤其适用于生物医学应用。
• Durable hydrogen bonded hydrogels
  申请人：Suprapolix B.V.

  公开号：US10358521B2

  公开（公告）日：2019-07-23

  This disclosure relates to new injectable hydrogel materials that consist of water gellants comprising linear hydrophilic polymers that comprise hydrogen bonding units in the backbone combined with cross-linkable end groups, resulting in dynamic yet firm hydrogel materials that are easily processable, are highly elastic, show adhesive properties and are self-healing and are especially suitable for biomedical applications.

  本公开涉及新型可注射水凝胶材料，它由亲水性线性聚合物组成的水凝胶剂构成，亲水性线性聚合物的骨架中含有氢键单元，并与可交联的末端基团相结合，从而形成动态而又牢固的水凝胶材料，这种材料易于加工、具有高弹性、粘合性和自愈合性，尤其适合生物医学应用。
• Supramolecular biodegradable polymer
  申请人：SupraPolix B.V.

  公开号：US10358522B2

  公开（公告）日：2019-07-23

  The present invention relates to a supramolecular biodegradable polymer comprising a quadruple hydrogen bonding unit (abbreviated herein as “4H-unit”), a biodegradable backbone and hard blocks and a process for preparing such a supramolecular biodegradable polymer. The supramolecular polymer is specifically suitable for biodegradable articles such as biomedical implants that need high strength and/or elasticity, e.g. medical implants in the cardio-vascular field.

  本发明涉及一种超分子可生物降解聚合物，该聚合物由四重氢键单元（在此简 称为 "4H-单元"）、可生物降解骨架和硬块组成，还涉及制备这种超分子可生物降 解聚合物的工艺。这种超分子聚合物特别适用于生物可降解物品，如需要高强度和/或高弹性的生物医学植入物，如心血管领域的医疗植入物。
• Organic Carbonates. IV.^1a,b,c Factors Affecting Formation of Homologous Cyclic Carbonates
  作者：SHALOM SAREL、LEO A. POHORYLES、RAPHAEL BEN-SHOSHAN

  DOI：10.1021/jo01094a010

  日期：1959.12