3-(苯基氨基)丙基硫酸盐 | 1198271-87-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 3-(苯基氨基)丙基硫酸盐
• 英文名称: 3-(phenylammonio)propyl sulfate
• 英文别名: 3-(Phenylazaniumyl)propyl sulfate；3-(phenylazaniumyl)propyl sulfate
• CAS: 1198271-87-2
• 化学式: C₉H₁₃NO₄S
• 分子量: 231.273
• InChiKey: GKGINUSBUUXXKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  84
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-(苯基氨基)丙基硫酸盐 在 potassium hydroxide 作用下， 以 水 为溶剂， 反应 0.25h， 以21 mg的产率得到1-苯基氮杂丁烷
  参考文献：
  名称：

  Microwave-assisted synthesis of azetidines in aqueous media

  摘要：

  Simple azetidines are synthesized in good to excellent yields and high purity via cyclization of 3-(ammonio nio)propyl sulfates derived from primary amines and the cyclic sulfate of 1,3-propanediol. A feature of this methodology includes the accelerated synthesis of azetidines in water under the influence of microwave-assisted heating. (C) 2009 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tetlet.2009.09.063
• 作为产物：
  描述：

  苯胺 、 1,3-丙二醇环硫酸酯 以 乙腈 为溶剂， 生成 3-(苯基氨基)丙基硫酸盐
  参考文献：
  名称：

  Microwave-assisted synthesis of azetidines in aqueous media

  摘要：

  Simple azetidines are synthesized in good to excellent yields and high purity via cyclization of 3-(ammonio nio)propyl sulfates derived from primary amines and the cyclic sulfate of 1,3-propanediol. A feature of this methodology includes the accelerated synthesis of azetidines in water under the influence of microwave-assisted heating. (C) 2009 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tetlet.2009.09.063

文献信息

• Microwave-assisted synthesis of azetidines in aqueous media
  作者：Brendan A. Burkett、Samuel Z. Ting、Gwendolyn C.S. Gan、Christina L.L. Chai

  DOI：10.1016/j.tetlet.2009.09.063

  日期：2009.11

  Simple azetidines are synthesized in good to excellent yields and high purity via cyclization of 3-(ammonio nio)propyl sulfates derived from primary amines and the cyclic sulfate of 1,3-propanediol. A feature of this methodology includes the accelerated synthesis of azetidines in water under the influence of microwave-assisted heating. (C) 2009 Elsevier Ltd. All rights reserved