1-nitrosodecane dimer | 99729-93-8

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氧氮鎓化合物
• 英文名称: 1-nitrosodecane dimer
• 英文别名: decyl-[decyl(oxido)amino]-oxoazanium
• CAS: 99729-93-8
• 化学式: C₂₀H₄₂N₂O₂
• 分子量: 342.566
• InChiKey: NFRXIVHEDTYQCI-UHFFFAOYSA-N

物化性质

• 沸点：
  454.2±28.0 °C(Predicted)
• 密度：
  0.893±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.74
• 重原子数：
  24.0
• 可旋转键数：
  18.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52.14
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  1-氨基癸烷 在 甲基三氧化铼(VII) 双氧水 作用下， 以 乙腈 为溶剂， 反应 0.5h， 以43%的产率得到癸醛醛肟
  参考文献：
  名称：

  甲基三氧铼催化过氧化氢氧化仲胺和伯胺

  摘要：

  用过氧化氢对仲胺和伯胺进行了甲基三氧铼催化氧化。仲胺的氧化以良好至极好的收率提供硝酮。苄胺被选择性氧化为肟，而具有 α-C-H 键的一般伯烷基胺生成肟、亚硝基二聚体和氧化偶氮化合物的混合物。

  DOI：

  10.1246/bcsj.70.877

文献信息

• Dimethyldioxirane oxidation of primary amines
  作者：Jack K. Crandall、Thierry Reix

  DOI：10.1021/jo00051a017

  日期：1992.12

  Several primary amines 2 have been oxidized with dimethyldioxirane (1) under a variety of conditions. Mixtures of dimeric nitrosoalkanes 4 and oximes 5 were typically obtained with solutions of the oxidant in excess. In several instances, nitrones 12 were found as byproducts in these reactions. In situ oxidations using oxone in buffered aqueous acetone solution also gave nitrosoalkanes 4 and oximes 3 as important products; in addition, oxaziridines 11 were obtained in significant amounts in biphasic procedures containing methylene chloride. The corresponding nitroalkanes 3 were not formed in major amounts in either oxidation procedure, unless large excesses of oxidant were used. These results are discussed in terms of the several competing processes which occur under the different reaction conditions.
• Methyltrioxorhenium-Catalyzed Oxidation of Secondary and Primary Amines with Hydrogen Peroxide
  作者：Shigekazu Yamazaki

  DOI：10.1246/bcsj.70.877

  日期：1997.4

  The methyltrioxorhenium-catalyzed oxidation of secondary amines and primary amines with hydrogen peroxide has been carried out. The oxidation of secondary amines afforded nitrones in good-to-excellent yield. Benzylamines were selectively oxidized to oximes, while general primary alkylamines possessing the α-C–H bond gave mixtures of oximes, nitroso dimers, and azoxy compounds.

  用过氧化氢对仲胺和伯胺进行了甲基三氧铼催化氧化。仲胺的氧化以良好至极好的收率提供硝酮。苄胺被选择性氧化为肟，而具有 α-C-H 键的一般伯烷基胺生成肟、亚硝基二聚体和氧化偶氮化合物的混合物。